Multifunctional cancer therapeutic nanodevices have been designed and synthesized using
the poly (amidoamine)(PAMAM) dendrimer as a carrier. Partial acetylation of the generation …

A saccharide-terminated generation 3 (G3) polyamidoamine (PAMAM) dendrimer was
synthesized as a drug carrier. Utilizing this dendritic platform, we have successfully …

Dendrimers have emerged as multifunctional carriers for targeted drug delivery, gene
delivery and imaging. Improving the functional versatility at the surface for carrying multiple …

In this work, we presented ternary nanoparticles [poly (carboxybetaine
methacrylate)(pCBMA)(peptide dendrimer-modified carbon dots (CD-D)/doxorubicin (DOX))] …

Ligand-mediated targeting of drugs especially in anticancer drug delivery is an effective
approach. Dendrimers, due to unique surface topologies, can be a choice in this context. In …

Targeted drug delivery is important in cancer therapy to decrease the systemic toxicity
resulting from nonspecific drug distribution and to enhance drug delivery efficiency. We have …

The functionalization of pH-sensitiveness and cellular targeting is a promising strategy to
fabricate drug delivery systems with high efficiency, high selectivity and low toxicity. In this …

We have synthesized a stable and clinically relevant nanodevice (cRGD-BT-ND; ND for
short) that exhibits superior binding to the biologic target αvβ3 integrins, when either …

We report the development of a lactobionic acid (LA)-modified multifunctional dendrimer-
based carrier system for targeted therapy of liver cancer cells overexpressing …

Chemotherapy is the first choice in the treatment of cancer and is always preferred to other
approaches such as radiation and surgery, but it has never met the need of patients for a …