Quantitative analysis of dynamic Gd‐DTPA enhancement in breast tumors using a permeability model
PS Tofts, B Berkowitz… - Magnetic resonance in …, 1995 - Wiley Online Library
The MRI signal enhancement in a breast tumor, measured as a function of time after a bolus
injection of Gd‐DTPA, may contain enough information to differentiate malignant from …
injection of Gd‐DTPA, may contain enough information to differentiate malignant from …
Measurement of vascular volume fraction and blood‐tissue permeability constants with a pharmacokinetic model: studies in rat muscle tumors with dynamic Gd‐DTPA …
MY Su, JC Jao, O Nalcioglu - Magnetic resonance in medicine, 1994 - Wiley Online Library
We propose a compartmental model to explain the signal enhancement curves following the
bolus injection of Gd‐DTPA. The model incorporates vascular volume fraction contribution …
bolus injection of Gd‐DTPA. The model incorporates vascular volume fraction contribution …
Dynamic contrast‐enhanced MRI using Gd‐DTPA: interindividual variability of the arterial input function and consequences for the assessment of kinetics in tumors
Gd‐DTPA kinetics in arterial blood was investigated by dynamic MRI in 47 patients with
malignant and benign mammary tumors. Signal enhancement was monitored for 10 min …
malignant and benign mammary tumors. Signal enhancement was monitored for 10 min …
Measurement of the blood‐brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts
PS Tofts, AG Kermode - Magnetic resonance in medicine, 1991 - Wiley Online Library
Leakage of Gd‐DTPA through a defective blood‐brain barrier is measured quantitatively
using dynamic MRI scanning, in which repeated scans are made after a bolus injection …
using dynamic MRI scanning, in which repeated scans are made after a bolus injection …
Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agents
E Henderson, J Sykes, D Drost… - Journal of Magnetic …, 2000 - Wiley Online Library
A technique for the simultaneous measurement of three vascular parameters: blood flow
(Fρ), blood volume (vb), and the capillary permeability‐surface area product (PSρ) in breast …
(Fρ), blood volume (vb), and the capillary permeability‐surface area product (PSρ) in breast …
Probing tumor microvascularity by measurement, analysis and display of contrast agent uptake kinetics
GJM Parker, J Suckling, SF Tanner… - Journal of Magnetic …, 1997 - Wiley Online Library
This paper describes a measurement protocol for acquiring quantitative dynamic MRI data
and novel analysis and display software (Magnetic Resonance Imaging Workbench …
and novel analysis and display software (Magnetic Resonance Imaging Workbench …
Dynamic MR imaging of the breast combined with analysis of contrast agent kinetics in the differentiation of primary breast tumours
S Mussurakis, DL Buckley, PJ Drew, JN Fox… - Clinical radiology, 1997 - Elsevier
Objective: To assess dynamic Gd-DTPA-enhanced magnetic resonance (MR) imaging in the
diagnosis of primary breast pathology, and to test the hypothesis that analysis of contrast …
diagnosis of primary breast pathology, and to test the hypothesis that analysis of contrast …
Method for quantitative mapping of dynamic MRI contrast agent uptake in human tumors
M Rijpkema, JHAM Kaanders… - Journal of Magnetic …, 2001 - Wiley Online Library
A method is presented for the acquisition and analysis of dynamic contrast‐enhanced (DCE)
MRI data, focused on the characterization of tumors in humans. Gadolinium (Gd) contrast …
MRI data, focused on the characterization of tumors in humans. Gadolinium (Gd) contrast …
Functional magnetic resonance of human breast tumors: diffusion and perfusion imaging
This review is focused on two relatively new developments in magnetic resonance imaging
(MRI) and their application to breast lesion characterization: diffusion and perfusion MRI …
(MRI) and their application to breast lesion characterization: diffusion and perfusion MRI …
Dynamic echo-planar imaging of the breast: experience in diagnosing breast carcinoma and correlation with tumor angiogenesis.
CA Hulka, WB Edmister, BL Smith, L Tan, DC Sgroi… - Radiology, 1997 - pubs.rsna.org
PURPOSE: To correlate quantitative echo-planar magnetic resonance (MR) imaging
measures of gadopentetate dimeglumine tumor uptake with histologic diagnoses and …
measures of gadopentetate dimeglumine tumor uptake with histologic diagnoses and …
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