Somatostatin-expressing inhibitory interneurons in cortical circuits

I Yavorska, M Wehr - Frontiers in neural circuits, 2016 - frontiersin.org
Cortical inhibitory neurons exhibit remarkable diversity in their morphology, connectivity, and
synaptic properties. Here, we review the function of somatostatin-expressing (SOM) …

Diversity and function of somatostatin-expressing interneurons in the cerebral cortex

T Riedemann - International journal of molecular sciences, 2019 - mdpi.com
Inhibitory interneurons make up around 10–20% of the total neuron population in the
cerebral cortex. A hallmark of inhibitory interneurons is their remarkable diversity in terms of …

Diversity and connectivity of layer 5 somatostatin-expressing interneurons in the mouse barrel cortex

MJ Nigro, Y Hashikawa-Yamasaki… - Journal of …, 2018 - Soc Neuroscience
Inhibitory interneurons represent 10–15% of the neurons in the somatosensory cortex, and
their activity powerfully shapes sensory processing. Three major groups of GABAergic …

Somatostatin and somatostatin-containing neurons in shaping neuronal activity and plasticity

M Liguz-Lecznar, J Urban-Ciecko… - Frontiers in neural circuits, 2016 - frontiersin.org
Since its discovery over four decades ago, somatostatin (SOM) receives growing scientific
and clinical interest. Being localized in the nervous system in a subset of interneurons …

Cortical somatostatin interneuron subtypes form cell-type-specific circuits

SJ Wu, E Sevier, D Dwivedi, GA Saldi, A Hairston, S Yu… - Neuron, 2023 - cell.com
The cardinal classes are a useful simplification of cortical interneuron diversity, but such
broad subgroupings gloss over the molecular, morphological, and circuit specificity of …

Neocortical somatostatin-expressing GABAergic interneurons disinhibit the thalamorecipient layer 4

H Xu, HY Jeong, R Tremblay, B Rudy - Neuron, 2013 - cell.com
Summary Subtypes of GABAergic interneurons (INs) are crucial for cortical function, yet their
specific roles are largely unknown. In contrast to supra-and infragranular layers, where most …

Visual representations by cortical somatostatin inhibitory neurons—selective but with weak and delayed responses

W Ma, B Liu, Y Li, ZJ Huang, LI Zhang… - Journal of …, 2010 - Soc Neuroscience
Somatostatin-expressing inhibitory (SOM) neurons in the sensory cortex consist mostly of
Martinotti cells, which project ascending axons to layer 1. Due to their sparse distribution, the …

Interneuron-specific signaling evokes distinctive somatostatin-mediated responses in adult cortical astrocytes

L Mariotti, G Losi, A Lia, M Melone… - Nature …, 2018 - nature.com
The signaling diversity of GABAergic interneurons to post-synaptic neurons is crucial to
generate the functional heterogeneity that characterizes brain circuits. Whether this diversity …

Somatostatin-expressing neurons in cortical networks

J Urban-Ciecko, AL Barth - Nature Reviews Neuroscience, 2016 - nature.com
Somatostatin-expressing GABAergic neurons constitute a major class of inhibitory neurons
in the mammalian cortex and are characterized by dense wiring into the local network and …

Hippocampal somatostatin interneurons, long-term synaptic plasticity and memory

E Honoré, A Khlaifia, A Bosson… - Frontiers in neural circuits, 2021 - frontiersin.org
A distinctive feature of the hippocampal structure is the diversity of inhibitory interneurons.
These complex inhibitory interconnections largely contribute to the tight modulation of …