Protective Effect of Alkaline Mineral Water on Calcium Oxalate‐Induced Kidney Injury in Mice

L Liu, C Lin, X Li, Y Cheng, R Wang… - Evidence‐Based …, 2023 - Wiley Online Library
Background. Kidney stone disease induces chronic renal insufficiency by crystal‐induced
renal tubular epithelial cell injury. It has been reported that the prevalence of kidney stone …

[HTML][HTML] Oral hydrogen-rich water alleviates oxalate-induced kidney injury by suppressing oxidative stress, inflammation, and fibrosis

Y Si, L Liu, J Cheng, T Zhao, Q Zhou, J Yu… - Frontiers in …, 2021 - frontiersin.org
Objective: To explore the theraputic effects and potential mechanisms of hydrogen-rich
water (HRW) against oxalate-induced kidney injury. Methods: The mouse model of Calcium …

Gallic acid ameliorates calcium oxalate crystal-induced renal injury via upregulation of Nrf2/HO-1 in the mouse model of stone formation

D Zhou, Y Wu, H Yan, T Shen, S Li, J Gong, G Li, H Mai… - Phytomedicine, 2022 - Elsevier
Background High prevalence and reoccurrence rate of nephrolithiasis bring about serious
socioeconomic and healthcare burden, necessitating the need of effective therapeutic …

Hydroxycitric acid inhibits renal calcium oxalate deposition by reducing oxidative stress and inflammation

X Liu, P Yuan, X Sun, Z Chen - Current molecular medicine, 2020 - ingentaconnect.com
Objective: The study aimed to evaluate the preventive effects of hydroxycitric acid (HCA) for
stone formation in the glyoxylate-induced mouse model. Materials and Methods: Male …

Kaempferol alleviates calcium oxalate crystal-induced renal injury and crystal deposition via regulation of the AR/NOX2 signaling pathway

P Yuan, X Sun, X Liu, G Hutterer, K Pummer, B Hager… - Phytomedicine, 2021 - Elsevier
Abstract Background Calcium oxalate (CaOx) crystal deposition and crystal-induced renal
tubular epithelial cell injury have been found to fundamentally contribute to the formation of …

[HTML][HTML] Catechin prevents the calcium oxalate monohydrate induced renal calcium crystallization in NRK-52E cells and the ethylene glycol induced renal stone …

W Zhai, J Zheng, X Yao, B Peng, M Liu, J Huang… - … and alternative medicine, 2013 - Springer
Background Reactive oxygen species play important roles in renal calcium crystallization. In
this study, we examined the effects of catechin, which have been shown to have antioxidant …

Curcumin ameliorates glyoxylate-induced calcium oxalate deposition and renal injuries in mice

Y Li, J Zhang, H Liu, J Yuan, Y Yin, T Wang, B Cheng… - Phytomedicine, 2019 - Elsevier
Background Nephrolithiasis is one of the most common and frequent urologic diseases
worldwide. Several pathophysiological mechanisms are involved in stone formation …

A polyherbal formulation attenuates hyperoxaluria-induced oxidative stress and prevents subsequent deposition of calcium oxalate crystals and renal cell injury in rat …

KS Bodakhe, KP Namdeo, KC Patra, L Machwal… - Chinese journal of …, 2013 - Elsevier
Introduction Cystone is an approved Ayurvedic polyherbal proprietary medicine used in
India for various urinary disorders, including urolithiasis. Aim To evaluate the protective …

Efficacy of chlorogenic acid against ethylene glycol-induced renal stone model: The role of NFKB-RUNX2-AP1-OSTERIX signaling pathway

K Hoseinynejad, SA Mard, Z Mansouri, Z Lamoochi… - Tissue and Cell, 2022 - Elsevier
Background and objective Renal tissue injuries by free radicals are an essential reason in
pathogenesis of urinary tract stones. Ethylene glycol is one of the toxic agents which can …

The mechanism of the preventive effect of Shen'an capsule on the calcium oxalate crystal‐induced early renal injury based on metabolomics

W Fan, J Hou, W Zhu, S Zhang, K Shao… - Biomedical …, 2018 - Wiley Online Library
Kidney stone disease is a worldwide metabolism‐associated disorder with a high incidence
of renal dysfunction. However, effective methods to prevent crystalline nephropathy are still …