The clinical spectrum of fungal disease ranges from localized, superficial infections of the
skin and mucous membranes to life-threatening, systemic infection (Table 1). Infection of the …

Background Infections caused by fungi can be important causes of morbidity and mortality in
certain patient populations, including those who are highly immunocompromised or critically …

In the history of discoveries of fungal pathogens, the nineteenth century has witnessed two
important events. The causal organism of a silkworm disease, muscardine, a fungus named …

Invasive fungal infection is a growing cause of morbidity and mortality in immunosuppressed
patients. Furthermore, the use of azole prophylaxis against Candida species has coincided …

Fungi are eukaryotic heterotrophs present in virtually every environment, with potentially
more than 5 million individual species (1). Despite this impressive biodiversity, only about …

Abstract Seminal work by Louis Pasteur revealed the contribution of fungi–yeasts and
microsporidia to agroindustry and disease in animals, respectively. More than 150 years …

The incidence of fungal infections is increasing at an alarming rate, presenting an enormous
challenge to healthcare professionals. This increase is directly related to the growing …

The last decade has brought significant advances in our understanding of antifungal
immunity, which offer hope for the development of novel immunotherapeutics. In this …

Invasive fungal infections are a significant health problem in immunocompromised patients.
The clinical manifestations vary and can range from colonization in allergic …

The history of mankind has been shaped by infections, more than by war and famine
together. At the same time, however, the development of society has had an equally …