Synergistic biomineralization phenomena created by a combinatorial nacre protein model system

EP Chang, T Roncal-Herrero, T Morgan, KE Dunn… - Biochemistry, 2016 - ACS Publications
In the nacre or aragonite layer of the mollusk shell, proteomes that regulate both the early
stages of nucleation and nano-to-mesoscale assembly of nacre tablets from mineral …

Functional prioritization and hydrogel regulation phenomena created by a combinatorial pearl-associated two-protein biomineralization model system

G Jain, M Pendola, YC Huang, J Juan Colas… - Biochemistry, 2017 - ACS Publications
In the nacre or aragonitic layer of an oyster pearl, there exists a 12-member proteome that
regulates both the early stages of nucleation and nanoscale-to-mesoscale assembly of …

Selective synergism created by interactive nacre framework-associated proteins possessing EGF and vWA motifs: Implications for mollusk shell formation

G Jain, M Pendola, YC Huang, D Gebauer… - Biochemistry, 2018 - ACS Publications
In the nacre layer of the Pinctada fucata oyster shell there exists a multimember proteome,
known as the framework family, which regulates the formation of the aragonite mesoscale …

A nacre protein forms mesoscale hydrogels that “hijack” the biomineralization process within a seawater environment

M Pendola, G Jain, A Davidyants, YC Huang… - …, 2016 - pubs.rsc.org
We examined the mineralization performance of a nacre protein, AP7, within seawater
mineralization assays that form aragonite and magnesium calcite. Under these conditions …

Nacre protein sequence compartmentalizes mineral polymorphs in solution

J Seto, A Picker, Y Chen, A Rao, JS Evans… - Crystal growth & …, 2014 - ACS Publications
The Japanese pearl oyster (Pinctada fucata) n16 framework matrix protein is an integral part
of the growth and formation of the mollusk shell biomineralization mechanism. It is a …

Nacre protein fragment templates lamellar aragonite growth

RA Metzler, JS Evans, CE Killian, D Zhou… - Journal of the …, 2010 - ACS Publications
Proteins play a major role in the formation of all biominerals. In mollusk shell nacre, complex
mixtures and assemblies of proteins and polysaccharides were shown to induce aragonite …

An oligomeric C-RING nacre protein influences prenucleation events and organizes mineral nanoparticles

I Perovic, A Verch, EP Chang, A Rao, H Cölfen… - Biochemistry, 2014 - ACS Publications
The mollusk shell nacre layer integrates mineral phases with macromolecular components
such as intracrystalline proteins. However, the roles performed by intracrystalline proteins in …

A nacre protein, n16. 3, self-assembles to form protein oligomers that dimensionally limit and organize mineral deposits

I Perovic, EP Chang, M Lui, A Rao, H Cölfen… - Biochemistry, 2014 - ACS Publications
The mollusk shell is a complex biological material that integrates mineral phases with
organic macromolecular components such as proteins. The role of proteins in the formation …

“Liquid-like” biomineralization protein assemblies: a key to the regulation of non-classical nucleation

JS Evans - CrystEngComm, 2013 - pubs.rsc.org
Over the past several decades, numerous studies have attempted to define the general role
that proteins play in the nucleation of biominerals in organisms. Recently, with the …

A crystal modulating protein from molluscan nacre that limits the growth of calcite in vitro

IW Kim, S Collino, DE Morse, JS Evans - Crystal growth & design, 2006 - ACS Publications
Protein-mediated biomineral formation and polymorph selection in the mollusk shell
involves the participation of a number of different proteins. One of these proteins, AP7, has …