Excess H2O2 contributes to myocardial reperfusion injury. We detail the effect of H2O2-
induced oxidant stress on the tricarboxylic acid (TCA) cycle in isolated heart muscle cells …

Oxidative stress induced by hydrogen peroxide (H2O2) may contribute to the pathogenesis
of ischemic‐reperfusion injury in the heart. For the purpose of investigating directly the injury …

Hydrogen peroxide (H2O2) may incite cardiac ischemia-reperfusion injury. We evaluate
herein the influence of H2O2-induced oxidative stress on heart muscle hexose metabolism …

Abstract Hydrogen peroxide (H2O2) overload may contribute to cardiac ischemia‐
reperfusion injury. We report utilization of a previously described cardiomyocyte model (J …

Oxidative stress is involved in mitochondrial apoptosis, and plays a critical role in ischemic
heart disease and cardiac failure. Exposure of cardiomyocytes to H2O2 leads to oxidative …

Ischemia-reperfusion injury induces oxidant stress, and the burst of reactive oxygen species
(ROS) production after reperfusion of ischemic myocardium is sufficient to induce cell death …

There is evidence that myocardial injury, as would occur on post-ischemic reperfusion, may
be caused by the generation of oxygen radicals, as well as by the induction of intracellular …

After a transient ischemic attack of the cardiac vascular system, reactive oxygen-derived free
radicals, including the superoxide (O2−•) and hydroxyl (• OH) radicals can be easily …

Cardiomyocyte hypertrophy and cell death are often observed in the end stages of heart
failure. The triggers of these two cellular processes are not known under most pathological …

OBJECTIVES This study was designed to test the hypothesis that cardiac myocytes have
greater vulnerability to oxidative stress compared with cardiac fibroblasts. BACKGROUND …