The clinical meaning of a cervical intraepithelial neoplasia grade 1 biopsy

PE Castle, JC Gage, CM Wheeler… - Obstetrics & …, 2011 - journals.lww.com
OBJECTIVE: To determine whether the diagnosis of cervical intraepithelial neoplasia (CIN)
grade 1 increases the risk of CIN 3 above what is observed for human papillomavirus (HPV) …

Prospective follow-up suggests similar risk of subsequent cervical intraepithelial neoplasia grade 2 or 3 among women with cervical intraepithelial neoplasia grade 1 …

JT Cox, M Schiffman, D Solomon - American journal of obstetrics and …, 2003 - Elsevier
Objective: The purpose of this study was to determine the risk of cumulative cervical
intraepithelial neoplasia (CIN) grade 2 or 3 according to initial colposcopy and directed …

An analysis of high-risk human papillomavirus DNA-negative cervical precancers in the ASCUS-LSIL Triage Study (ALTS)

PE Castle, JT Cox, J Jeronimo, D Solomon… - Obstetrics & …, 2008 - journals.lww.com
OBJECTIVE: To describe women diagnosed with cervical intraepithelial neoplasia-grade 3
(CIN-3) diagnosed over the 2-year duration of the atypical squamous cells of undetermined …

High prevalence of HPV16 and high‐grade cytology in women undergoing active surveillance for cervical intraepithelial neoplasia grade 2

RK Damgaard, D Jenkins, MH Stoler… - Acta Obstetricia et …, 2023 - Wiley Online Library
Introduction Many countries have adopted active surveillance in women with cervical
intraepithelial neoplasia grade 2 (CIN2), leaving the lesion untreated. However, there is a …

Evidence for frequent regression of cervical intraepithelial neoplasia–grade 2

PE Castle, M Schiffman, CM Wheeler… - Obstetrics & …, 2009 - journals.lww.com
OBJECTIVE: To estimate the fraction of cervical intraepithelial neoplasia 2 (CIN 2) that might
regress if untreated using data from the Atypical Squamous Cells of Undetermined …

Predictor factors for conservative management of cervical intraepithelial neoplasia grade 2: Cytology and HPV genotyping

A Salvadó, E Miralpeix, JM Solé-Sedeno, N Kanjou… - Gynecologic …, 2021 - Elsevier
Objective The purpose of this study was to evaluate the role of HPV genotyping and
previous cytology result to predict the evolution of CIN2 histological lesions managed …

A prospective study of biopsy-confirmed cervical intraepithelial neoplasia grade 1: colposcopic, cytological, and virological risk factors for progression

MD Greenberg, R Reid, M Schiffman… - Journal of lower …, 1999 - journals.lww.com
Objectives: The objective of this prospective study of histologically confirmed cervical
intraepithelial neoplasia (CIN)(including equivocal CIN1) was to determine risk factors for …

The relationship of community biopsy-diagnosed cervical intraepithelial neoplasia grade 2 to the quality control pathology-reviewed diagnoses: an ALTS report

PE Castle, MH Stoler, D Solomon… - American journal of …, 2007 - academic.oup.com
We examined the predictors (cytologic interpretations, pathology review, human
papillomavirus [HPV] testing results, and colposcopic impressions) of precancer among 545 …

High-grade cervical intraepithelial neoplasia detected by colposcopy-directed or random biopsy relative to age, cytology, human papillomavirus 16, and lesion size

Q Chen, H Du, RG Pretorius, C Wang… - Journal of lower …, 2016 - journals.lww.com
Objective The aim of the study was to determine whether p16 positive/cervical intraepithelial
neoplasia (CIN) 2, 3, and cancer (p16+ CIN 2/3+) detected by colposcopy-directed or …

Comparison of predictors for high-grade cervical intraepithelial neoplasia in women with abnormal smears

A Szarewski, L Ambroisine, L Cadman, J Austin… - … Biomarkers & Prevention, 2008 - AACR
Background: The detection of high-risk human papillomavirus (HPV) DNA provides higher
sensitivity but lower specificity than cytology for the identification of high-grade cervical …