Aging is accompanied by many physiological changes including those in the immune
system. These changes are designated as immunosenescence indicating that age induces …

During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

The immune system is the most important protective physiological system of the organism. It
has many connections with other systems and is, in fact, often considered as part of the …

Aging of the immune system, or immunosenescence, is a complex subject best defined as a
decline in cell-mediated immunity, particularly with respect to T cell function. Paradoxically …

As is apparent from the many contributions to this Special Issue of the Journal, the impact of
age on immunity is nefarious, with all manner of dysregulated responses attributed to …

Chronic low-grade inflammation has a key role in the aging process, a state called
inflammaging. It is known that the chronic inflammatory condition generates counteracting …

Aging is a complex phenomenon the cause of which is not fully understood, despite the
plethora of theories proposed to explain it. As we age, changes in essentially all …

In the classic sense, immunity is the ability of an organism to resist disease. On the one
hand, we must distinguish between age and disease; on the other hand, the interaction …

The functional competence of the immune system gradually declines with aging, a process
called immunosenescence. The age-related remodelling of the immune system affects both …

Evolutionary pressure has selected individuals with traits that allow them to survive to
reproduction, without consideration of the consequences for the post‐child rearing years …