Rationale In schizophrenia, attentional disturbance is a core feature which may not only
accompany the disorder, but may precede the onset of psychiatric symptoms. Objectives The …

BACKGROUND: Attentional deficits accompany many psychiatric disorders, underscoring
the need for rodent models of attention to screen novel therapeutic agents and characterize …

Schizophrenia is associated with impaired attention. The top-down control of attention,
defined as the ability to guide and refocus attention in accordance with internal goals and …

Schizophrenia patients suffer from cognitive impairments that are not satisfactorily treated by
currently available medications. Cognitive dysfunction in schizophrenia encompasses …

Rationale. The developmental history and application of the 5-choice serial reaction time
task (5CSRTT) for measuring effects of drugs and other manipulations on attentional …

Disturbances in attentional processes are a common feature of several psychiatric disorders
such as schizophrenia, attention deficit/hyperactivity disorder and Huntington's disease. The …

Impaired attention is evident in several neurological and psychiatric disorders. In the present
study, attentional capabilities were measured in the operant five-choice serial reaction time …

Schizophrenia is widely thought to involve deficits of attention. However, the term “attention”
can be defined so broadly that impaired performance on virtually any task could be …

Attentional dysfunction in schizophrenia (SZ) is a core deficit that contributes to multiple
cognitive deficits and the resulting functional disability. However, developing procognitive …

Currently accepted treatments for schizophrenia can effectively control positive symptoms
but have limited impact on cognitive deficits in schizophrenia. The purpose of these …