Six patients with de novo acute myeloid leukemia (AML) and at (2; 3)(p15–21; q26–27) were
identified among approximately 1000 cases enrolled in the GIMEMA trial. The t (2; 3) was …

EVI is a proto-oncogene that is activated in acute myeloid leukemia with chromosomal
rearrangements that map to chromosome 3q26. We previously reported the …

We previously reported a recurrent t (3; 8)(q26; q24) translocation involving EVI1 in five
patients with myelodysplastic syndrome or acute myeloid leukemia. Here we report the …

The EVI1 proto-oncogene encodes a nuclear zinc finger protein that acts as a transcription
repressor factor. In myeloid leukemia it is often activated by chromosomal rearrangements …

Several chromosomal rearrangements involving band 3q26 are known to induce EVI1
overexpression. They include inv (3)(q21q26), t (3; 3)(q21; q26), t (3; 21)(q26; q22) and t (3; …

The Evi-1 zinc-finger protein gene is normally not expressed in hematopoietic cells.
However, high Evi-1 mRNA expression has been reported in mouse myeloblastic …

Chromosomal translocations involving the EVI1 locus are a recurrent finding in myeloid
leukemia and are associated with poor prognosis. In this study, we performed a detailed …

The murine Evi-1 gene encodes a protein that has multiple 28-amino acid repeats
containing the consensus sequence found in the zinc finger domains of many transcriptional …

Fluorescence in situ hybridization examination of a pediatric AML patient whose bone
marrow cells carried trisomy 4 and FLT3-ITD mutation, demonstrated that part of the RUNX1 …

3 Archimbaud E, Charrin C, Magaud JP, Campos L, Thomas X, Fiere D, Rimokh R. Clinical
and biological characteristics of adult de novo and secondary acute myeloid leukemia with …