Targeted modulation of immune cells and tissues using engineered biomaterials
P Yousefpour, K Ni, DJ Irvine - Nature reviews bioengineering, 2023 - nature.com
Therapies modulating the immune system offer the prospect of treating a wide range of
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
conditions including infectious diseases, cancer and autoimmunity. Biomaterials can …
Advancing immunotherapy using biomaterials to control tissue, cellular, and molecular level immune signaling in skin
Immunotherapies have been transformative in many areas, including cancer treatments,
allergies, and autoimmune diseases. However, significant challenges persist in extending …
allergies, and autoimmune diseases. However, significant challenges persist in extending …
Delivery Route Considerations for Designing Antigen‐Specific Biomaterial Strategies to Combat Autoimmunity
MA Ackun-Farmmer, CM Jewell - Advanced NanoBiomed …, 2023 - Wiley Online Library
Disease‐modifying drugs and biologics used to treat autoimmune diseases, although
promising, are non‐curative. As the field moves toward development of new approaches to …
promising, are non‐curative. As the field moves toward development of new approaches to …
Macroscale biomaterials strategies for local immunomodulation
The immune system plays key roles in tissue homeostatic and disease processes, and
manipulation of innate and adaptive immune responses is of great promise for a wide array …
manipulation of innate and adaptive immune responses is of great promise for a wide array …
Unlocking Transplant Tolerance with Biomaterials
JPA Pham, MM Coronel - Advanced Healthcare Materials, 2024 - Wiley Online Library
For patients suffering from organ failure due to injury or autoimmune disease, allogeneic
organ transplantation with chronic immunosuppression is considered the gold standard in …
organ transplantation with chronic immunosuppression is considered the gold standard in …
Harnessing Biomaterials to Study and Direct Antigen-Specific Immunotherapy
C Edwards, ST Carey, CM Jewell - ACS Applied Bio Materials, 2023 - ACS Publications
Immunotherapies are an evolving treatment paradigm for addressing cancer, autoimmunity,
and infection. While exciting, most of the existing therapies are limited by their specificity─ …
and infection. While exciting, most of the existing therapies are limited by their specificity─ …
Combinatorial drug delivery approaches for immunomodulation
JM Stewart, BG Keselowsky - Advanced drug delivery reviews, 2017 - Elsevier
Immunotherapy has been widely explored for applications to both augment and suppress
intrinsic host immunity. Clinical achievements have seen a number of immunotherapeutic …
intrinsic host immunity. Clinical achievements have seen a number of immunotherapeutic …
Engineering antigen-presenting cells for immunotherapy of autoimmunity
Autoimmune diseases are burdensome conditions that affect a significant fraction of the
global population. The hallmark of autoimmune disease is a host's immune system being …
global population. The hallmark of autoimmune disease is a host's immune system being …
Biomaterials as local niches for immunomodulation
K Adu-Berchie, DJ Mooney - Accounts of chemical research, 2020 - ACS Publications
Conspectus A major function of the immune system is to detect threat from foreign invaders,
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
tissue damage, or cancer and to mount a counter response that resolves the threat, restores …
[HTML][HTML] Emerging strategies to bypass transplant rejection via biomaterial-assisted immunoengineering: Insights from islets and beyond
S Abbaszadeh, V Nosrati-Siahmazgi, K Musaie… - Advanced Drug Delivery …, 2023 - Elsevier
Novel transplantation techniques are currently under development to preserve the function
of impaired tissues or organs. While current technologies can enhance the survival of …
of impaired tissues or organs. While current technologies can enhance the survival of …