Macroscale biomaterials, such as preformed implantable scaffolds and injectable soft
materials, possess powerful synergies with anti-cancer immunotherapies. Immunotherapies …

Immunotherapies for cancer have progressed enormously over the past few decades, and
hold great promise for the future. The successes of these therapies, with some patients …

Conditions in which abnormal or excessive immune responses exist, such as autoimmune
diseases (ADs), graft-versus-host disease, transplant rejection, and hypersensitivity …

Objectives Biomaterials are routinely used in clinical applications. A key to the clinical
success of implanted biomaterials is not eliciting detrimental immune responses. In this …

Cancer immunotherapies have revolutionized the treatment of numerous cancers, with
exciting results often superior to conventional treatments, such as surgery and …

Autoimmune diseases, such as celiac disease, multiple sclerosis, and type 1 diabetes, are
leading causes of morbidity and mortality in the United States. In these disease states …

As regenerative medicine matures as a field, more promising technologies are being
translated from the benchtop to the clinic. However, many of these strategies are designed …

Tissue repair/regeneration, after implantation or injury, involves comprehensive
physiological processes wherein immune responses play a crucial role to enable tissue …

Cancer immunotherapy, as a paradigm shift in cancer treatment, has recently received
tremendous attention. The active cancer vaccination, immune checkpoint blockage (ICB) …

Biomaterial scaffolds that enrich and modulate immune cells in situ can form the basis for
potent immunotherapies to elicit immunity or reëstablish tolerance. Here, the authors explore …