Biomimetic tissue engineering: tuning the immune and inflammatory response to implantable biomaterials

F Taraballi, M Sushnitha, C Tsao… - Advanced …, 2018 - Wiley Online Library
Regenerative medicine technologies rely heavily on the use of well‐designed biomaterials
for therapeutic applications. The success of implantable biomaterials hinges upon the ability …

Stimuli‐responsive biomaterials for vaccines and immunotherapeutic applications

N Pacifici, A Bolandparvaz, JS Lewis - Advanced therapeutics, 2020 - Wiley Online Library
The immune system is the key target for vaccines and immunotherapeutic approaches
aimed at blunting infectious diseases, cancer, autoimmunity, and implant rejection …

Biomaterials as tools to decode immunity

HB Eppler, CM Jewell - Advanced Materials, 2020 - Wiley Online Library
The immune system has remarkable capabilities to combat disease with exquisite selectivity.
This feature has enabled vaccines that provide protection for decades and, more recently …

Interfacing biomaterials with synthetic T cell immunity

FY Su, QD Mac, A Sivakumar… - Advanced healthcare …, 2021 - Wiley Online Library
The clinical success of cancer immunotherapy is providing exciting opportunities for the
development of new methods to detect and treat cancer more effectively. A new generation …

Engineering synthetic vaccines using cues from natural immunity

DJ Irvine, MA Swartz, GL Szeto - Nature materials, 2013 - nature.com
Vaccines aim to protect against or treat diseases through manipulation of the immune
response, promoting either immunity or tolerance. In the former case, vaccines generate …

[HTML][HTML] Emerging immunomodulatory strategies for cell therapeutics

CYX Chua, AY Jiang, T Eufrásio-da-Silva… - Trends in …, 2023 - cell.com
Cellular therapies are poised to transform the field of medicine by restoring dysfunctional
tissues and treating various diseases in a dynamic manner not achievable by conventional …

Engaging adaptive immunity with biomaterials

C Mora-Solano, JH Collier - Journal of materials chemistry B, 2014 - pubs.rsc.org
Adaptive immune responses, characterized by T cells and B cells engaging and responding
to specific antigens, can be raised by biomaterials containing proteins, peptides, and other …

[HTML][HTML] Biomaterial-driven immunomodulation: cell biology-based strategies to mitigate severe inflammation and sepsis

JJM Lasola, H Kamdem, MW McDaniel… - Frontiers in …, 2020 - frontiersin.org
Inflammation is an essential component of a wide variety of disease processes and
oftentimes can increase the deleterious effects of a disease. Finding ways to modulate this …

Advanced biomaterials for cell‐specific modulation and restore of cancer immunotherapy

S Ruan, Y Huang, M He, H Gao - Advanced Science, 2022 - Wiley Online Library
The past decade has witnessed the explosive development of cancer immunotherapies.
Nevertheless, low immunogenicity, limited specificity, poor delivery efficiency, and off‐target …

Directing immunomodulation using biomaterials for endogenous regeneration

Y Yu, RX Wu, Y Yin, FM Chen - Journal of Materials Chemistry B, 2016 - pubs.rsc.org
Stem cell therapy and tissue engineering hold considerable potential for innovative and
transformative strategies to repair damaged tissue form and function. Although many …