Relationship between adiponectin, obesity and insulin resistance

GA Balsan, JLC Vieira, AM Oliveira… - Revista da Associação …, 2015 - SciELO Brasil
Objectives: the conditions of obesity and overweight pose a major risk for a number of
comorbidities, including clinical syndromes resulting from atherosclerotic disease. Recent …

Beneficial effects of adiponectin on glucose and lipid metabolism and atherosclerotic progression: mechanisms and perspectives

H Yanai, H Yoshida - International journal of molecular sciences, 2019 - mdpi.com
Circulating adiponectin concentrations are reduced in obese individuals, and this reduction
has been proposed to have a crucial role in the pathogenesis of atherosclerosis and …

Adiponectin: from obesity to cardiovascular disease

C Antoniades, AS Antonopoulos, D Tousoulis… - obesity …, 2009 - Wiley Online Library
Adiponectin is an adipokine whose biosynthesis is deranged in obesity and diabetes
mellitus, predisposing to atherosclerosis. Evidence suggests that adiponectin has anti …

Evidence of a causal relationship between high serum adiponectin levels and increased cardiovascular mortality rate in patients with type 2 diabetes

L Ortega Moreno, M Copetti, A Fontana… - Cardiovascular …, 2016 - Springer
Background Despite its beneficial role on insulin resistance and atherosclerosis,
adiponectin has been repeatedly reported as an independent positive predictor of …

Prognostic value of adiponectin for cardiovascular disease and mortality

JM Dekker, T Funahashi, G Nijpels… - The Journal of …, 2008 - academic.oup.com
Context: Low adiponectin concentrations are associated with the presence of an adverse
cardiovascular disease (CVD) risk profile. Objective: We studied the predictive value of …

Adiponectin and mortality in patients undergoing coronary angiography

S Pilz, H Mangge, B Wellnitz, U Seelhorst… - The Journal of …, 2006 - academic.oup.com
Context: The adipokine adiponectin has been suggested to protect against coronary artery
disease (CAD). However, studies addressing the association between adiponectin and …

The clinical implications of blood adiponectin in cardiometabolic disorders

LC Chang, KC Huang, YW Wu, HL Kao… - Journal of the Formosan …, 2009 - Elsevier
Adipose tissue is now accepted by the scientific and medical community to be a genuine
endocrine organ, in addition to its classical role as an energy store. Adiponectin is one of the …

Adiponectin and risk of coronary heart disease in older men and women

JR Kizer, JI Barzilay, LH Kuller… - The Journal of Clinical …, 2008 - academic.oup.com
Context: Despite established insulin-sensitizing and antiatherogenic preclinical effects,
epidemiological investigations of adiponectin have yielded conflicting findings, and its …

Plasma adiponectin levels are associated with insulin resistance, but do not predict future risk of coronary heart disease in women

DA Lawlor, G Davey Smith, S Ebrahim… - The Journal of …, 2005 - academic.oup.com
Context: Low adiponectin levels predict type 2 diabetes, and one prospective study in men
reported its independent prediction of vascular events. Many observers thus already …

Plasma adiponectin in overweight, nondiabetic individuals with or without insulin resistance

BI Shand, RS Scott, PA Elder… - Diabetes, Obesity and …, 2003 - Wiley Online Library
Aim: Adiponectin is a protein produced exclusively by adipocytes with putative insulin‐
sensitizing and anti‐atherogenic properties. This cross‐sectional study investigated the …