[HTML][HTML] Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

KZ Latt, K Honda, M Thiri, Y Hitomi, Y Omae, H Sawai… - Scientific reports, 2018 - nature.com
The associations of single nucleotide polymorphisms (SNPs) in PLA2R1 and HLA-DQA1, as
well as HLA-DRB1* 15: 01-DQB1* 06: 02 haplotype with idiopathic membranous …

Analysis of PLA2R1 and HLA-DQA1 sequence variants in Japanese patients with idiopathic and secondary membranous nephropathy

H Kaga, A Komatsuda, A Omokawa, S Okuyama… - Clinical and …, 2018 - Springer
Background Several recent studies in patients with idiopathic membranous nephropathy
(iMN) from Western and Asian counties showed that some single nucleotide polymorphisms …

Risk HLA-DQA1 and PLA2R1 Alleles in Idiopathic Membranous Nephropathy

HC Stanescu, M Arcos-Burgos, A Medlar… - … England Journal of …, 2011 - Mass Medical Soc
Background Idiopathic membranous nephropathy is a major cause of the nephrotic
syndrome in adults, but its etiologic basis is not fully understood. We investigated the genetic …

[HTML][HTML] High-density Association Mapping and Interaction Analysis of PLA2R1 and HLA Regions with Idiopathic Membranous Nephropathy in Japanese

M Thiri, K Honda, K Kashiwase, A Mabuchi, H Suzuki… - Scientific reports, 2016 - nature.com
Although recent studies showed anti-PLA2R antibody plays a crucial role in idiopathic
membranous nephropathy (IMN), detailed HLA mapping and interaction between the HLA …

[PDF][PDF] PLA2R1 and HLA-DQA1 gene variations in idiopathic membranous nephropathy in South China

F Wang, TT Wang, XW Liang, JD Lu, QH Xie… - Ann Acad Med …, 2021 - annals.edu.sg
Introduction: Associations of variations in PLA2R1 and HLA-DQA1 genes with susceptibility
to idiopathic membranous nephropathy (IMN) have been well documented. Association with …

Interaction between PLA2R1 and HLA‐DQA1 variants contributes to the increased genetic susceptibility to membranous nephropathy in Western China

W Wang, S Fan, G Li, AY Wang, D Hong, X Zhong… - …, 2019 - Wiley Online Library
Aim Recent studies showed that single nucleotide polymorphisms (SNP) within the
phospholipase A2 receptor (PLA2R1) and human leukocyte antigen complex class II HLA …

Association of 10 Polymorphisms in PLA2R1 and HLA DQA1 Genes with Primary Membranous Nephropathy Risk: A Meta-Analysis and a Meta-Regression

T Dhaouadi, A Riahi, TB Abdallah… - Biomarker …, 2024 - journals.sagepub.com
Background: Although, several studies have assessed the association of the phospholipase
A2 receptor (PLA2R) and HLA-DQA1 SNPs with primary membranous nephropathy (PMN) …

Genetic risk variants for membranous nephropathy: extension of and association with other chronic kidney disease aetiologies

P Sekula, Y Li, HC Stanescu, M Wuttke… - Nephrology Dialysis …, 2017 - academic.oup.com
Background: Membranous nephropathy (MN) is a common cause of nephrotic syndrome in
adults. Previous genome-wide association studies (GWAS) of 300 000 genotyped variants …

[HTML][HTML] The association between variants in PLA2R and HLA-DQA1 and renal outcomes in patients with primary membranous nephropathy in Western China

S Fan, Q Wang, AY Wang, P Zhang, X Zhong… - BMC Medical …, 2021 - Springer
Abstract Background Both Genome-wide associations and our previous study have shown
that single nucleotide polymorphisms (SNPs) of M-type phospholipase A2 receptor (PLA2R) …

[HTML][HTML] Single-nucleotide polymorphism rs4664308 in PLA2R1 gene is associated with the risk of idiopathic membranous nephropathy: a meta-analysis

M Yoshikawa, K Asaba - Scientific Reports, 2020 - nature.com
Although many studies investigated the associations between single-nucleotide
polymorphisms (SNPs) in the M-type phospholipase A2 receptor-1 (PLA2R1) gene and …