Detailed structural and assembly model of the type II secretion pilus from sparse data
Many Gram-negative bacteria secrete specific proteins via the type II secretion systems
(T2SS). These complex machineries share with the related archaeal flagella and type IV …
(T2SS). These complex machineries share with the related archaeal flagella and type IV …
Polar N-terminal residues conserved in type 2 secretion pseudopilins determine subunit targeting and membrane extraction steps during fibre assembly
J Santos-Moreno, A East, I Guilvout, N Nadeau… - Journal of molecular …, 2017 - Elsevier
Bacterial type 2 secretion systems (T2SS), type 4 pili, and archaeal flagella assemble fibres
from initially membrane-embedded pseudopilin and pilin subunits. Fibre subunits are made …
from initially membrane-embedded pseudopilin and pilin subunits. Fibre subunits are made …
Distinct docking and stabilization steps of the pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers
The closely related bacterial type II secretion (T2S) and type IV pilus (T4P) systems are
sophisticated machines that assemble dynamic fibers promoting protein transport, motility, or …
sophisticated machines that assemble dynamic fibers promoting protein transport, motility, or …
Pseudopilin residue E5 is essential for recruitment by the type 2 secretion system assembly platform
M Nivaskumar, J Santos‐Moreno… - Molecular …, 2016 - Wiley Online Library
Type II secretion systems (T2SSs) promote secretion of folded proteins playing important
roles in nutrient acquisition, adaptation and virulence of Gram‐negative bacteria. Protein …
roles in nutrient acquisition, adaptation and virulence of Gram‐negative bacteria. Protein …
Architecture of the type II secretion and type IV pilus machineries
M Ayers, PL Howell, LL Burrows - Future microbiology, 2010 - Taylor & Francis
Motility and protein secretion are key processes contributing to bacterial virulence. A wealth
of phylogenetic, biochemical and structural evidence support the hypothesis that the widely …
of phylogenetic, biochemical and structural evidence support the hypothesis that the widely …
Modeling pilus structures from sparse data
Bacterial Type II secretion systems (T2SS) and type IV pili (T4P) biogenesis machineries
share the ability to assemble thin filaments from pilin protein subunits in the plasma …
share the ability to assemble thin filaments from pilin protein subunits in the plasma …
Prime time for minor subunits of the type II secretion and type IV pilus systems
LL Burrows - Molecular microbiology, 2012 - Wiley Online Library
The type II secretion system (T2SS) exports folded proteins from the periplasms of Gram‐
negative bacteria. The type IV pilus system (T4PS) is a multifunctional machine used for …
negative bacteria. The type IV pilus system (T4PS) is a multifunctional machine used for …
[HTML][HTML] The type II secretion system–a dynamic fiber assembly nanomachine
M Campos, DA Cisneros, M Nivaskumar… - Research in …, 2013 - Elsevier
Type II secretion systems (T2SSs) share common origins and structure with archaeal flagella
(archaella) and pili, bacterial competence systems and type IV pili. All of these systems use …
(archaella) and pili, bacterial competence systems and type IV pili. All of these systems use …
Structure of an essential type IV pilus biogenesis protein provides insights into pilus and type II secretion systems
Type IV pili (T4Ps) are long cell surface filaments, essential for microcolony formation, tissue
adherence, motility, transformation, and virulence by human pathogens. The …
adherence, motility, transformation, and virulence by human pathogens. The …
Heterologous assembly of type IV pili by a type II secretion system reveals the role of minor pilins in assembly initiation
DA Cisneros, G Pehau‐Arnaudet… - Molecular …, 2012 - Wiley Online Library
In G ram‐negative bacteria, type IV pilus assembly (T4PS) and type II secretion (T2SS)
systems polymerize inner membrane proteins called major pilins or pseudopilins …
systems polymerize inner membrane proteins called major pilins or pseudopilins …