Pneumococcal disease in the elderly: what is preventing vaccine efficacy?

JB Rubins, EN Janoff - Drugs & aging, 2001 - Springer
The effective prevention of Streptococcus pneumoniae infection has a renewed priority in an
era in which the emergence of antibacterial-resistant strains has the potential to further …

Pneumococcal infection and vaccination in the elderly

C Vlasich - Vaccine, 2001 - Elsevier
The burden of pneumococcal disease among elderly people is not widely known. In most
countries, the annual incidence of invasive pneumococcal disease in elderly people is most …

Clinical efficacy of pneumococcal vaccine in the elderly: a randomized, single-blind population-based trial

I Koivula, M Stén, M Leinonen, PH Mäkelä - The American journal of …, 1997 - Elsevier
PURPOSE: To study the efficacy of pneumococcal capsular polysaccharide vaccine among
the elderly by use of a population-based intervention in one township, Varkaus, Eastern …

Pneumococcal vaccination for older adults: the first 20 years

DS Fedson - Drugs & aging, 1999 - Springer
During the 20 years following its licensure, pneumococcal vaccine has not been widely
used. Although the vaccine was shown to be efficacious in South African gold miners …

Advances in pneumococcal vaccines: what are the advantages for the elderly?

A Vila-Córcoles - Drugs & aging, 2007 - Springer
Streptococcus pneumoniae causes considerable morbidity and mortality in the elderly.
There are three established approaches to pneumococcal vaccination: polysaccharide …

[HTML][HTML] Preventing pneumococcal disease in the elderly: recent advances in vaccines and implications for clinical practice

A Vila-Corcoles, O Ochoa-Gondar - Drugs & aging, 2013 - Springer
Streptococcus pneumoniae remains a major cause of morbidity and mortality throughout the
world. To date, after the introduction of routine childhood immunization, elderly people (ie …

Pneumococcal vaccination and revaccination of older adults

AS Artz, WB Ershler, DL Longo - Clinical microbiology reviews, 2003 - Am Soc Microbiol
As individuals advance in age, the risk of infection, bacteremia, and mortality caused by
Streptococcus pneumoniae rises. Retrospective data demonstrate that the licensed …

Pneumococcal vaccination of elderly adults: new paradigms for protection

S Plotkin, LA Jackson, EN Janoff - Clinical Infectious Diseases, 2008 - academic.oup.com
Pneumococcal polysaccharide vaccine has been licensed for use in the United States for>
30 years, and two-thirds of the elderly population in the United States have received this …

Pneumococcal vaccine in the elderly: a useful but forgotten vaccine

C Chidiac, F Ader - Aging clinical and experimental research, 2009 - Springer
Pneumococcal disease in the elderly is a major concern emphasizing the need for
prevention. The review focuses on a literature-based analysis of the efficacy (“does the …

Pneumonia immunization in older adults: review of vaccine effectiveness and strategies

U Assaad, I El-Masri, J Porhomayon… - Clinical interventions in …, 2012 - Taylor & Francis
Vaccination remains the primary preventive strategy in the elderly against Streptococcus
pneumoniae and influenza infections. The effectiveness of this strategy in preventing …