Context: Cancer is the leading cause of death in the human population, ensuing from the
accumulation of damage to genetic materials and affecting various parts of the organs. This …

Aim: Until now, identification of drug targets for treatment of patients with specific stages of
colorectal cancer (CRC) has remained a challenging field of research. Herein, we aimed to …

Colorectal cancer (CRC) is a heterogeneous disease with changes in the genetic and
epigenetic levels of various genes. The molecular assessment of CRC is gaining increasing …

Colorectal cancer (CRC) is the third most common malignancy and one of the leading
causes of cancer-related death among men worldwide. CRC is a multifactor digestive …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Colorectal cancer (CRC) represents one of the most common cancers worldwide, with a
high mortality rate despite the decreasing incidence and new diagnostic and therapeutic …

Abstract Background The Wnt signaling pathway is a complex network of protein interactions
that functions most commonly in embryonic development and cancer, but is also involved in …

The Wnt/β-catenin signaling pathway is highly conservative. β-catenin is the key molecule in
this pathway. The β-catenin target genes regulate cell proliferation and apoptosis. Since Wnt …

Colorectal cancer (CRC) is the third most commonly detected cancer with a serious global
health issue. The rates for incidence and mortality for CRC are alarming, especially since …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …