In a population of cultured rat liver epithelial cells transformed by 11 brief treatments with N-
methyl-N′-nitro-N-nitrosoguanidine, 9% of the cells stained intensely for γ-glutamyl …

The relationship between γ-glutamyl transpeptidase (GGT) and malignant cell
transformation was analyzed in malignant and nonmalignant culture epithelial cell lines …

The presence of gamma-glutamyl transpeptidase (GGT) in focal nodules of hepatocytes is a
commonly used marker for the identification of preneoplastic cell populations. Female …

Hepatocytes isolated as a relatively pure population from normal adult rats were maintained
in primary monolayer culture for 4 to 7 days on plastic dishes. Factors affecting activity of γ …

The utility of γ-glutamyl transpeptldase (γ-GT) as a positive in vitro marker for isolated
hepatocytes derived from chemical carclnogen-induced presumptive premalignant and …

A continuously dividing but non-transformed rat cell line was transformed by ras oncogenes
and by aflatoxin. Transformed lines grew as solid tumours in nude mice with a short latency …

In rat chemical hepatocarcinogenesis models, the hepatocytes in the preneoplastic/
neoplastic nodules characteristically demonstrate common biochemical changes including …

To help clarify whether elevation of γ-glutamyltranspeptidase (GGT) in hepatocytes is
associated with particular pattern (s) of liver differentiation, adult rat heptocytes in primary …

Rat hepatocytes maintained for up to 6 days in primary culture were used to test a variety of
xenobiotics and steroids for effects on the activity of γ-glutamyl transpepti dase (GGT) in …

The appearance of γ-glutamyl transpeptidase (GGT) in focal areas of hepatocytes is a widely
used histochemical marker for the identification of preneoplastic cell populations. The …