Chronic neuroinflammation is a key pathological hallmark of multiple sclerosis (MS) that
suggests that resolution of inflammation by specialized proresolving molecules is …

Background Autoimmune diseases, like multiple sclerosis, are triggered by uncontrolled
activation of cells of the immune system against self-antigen present, for instance, in the …

Abstract Annexin A1 (AnxA1) is recognized as an endogenous anti-inflammatory molecule.
However, its effects on the adaptive immune response and, in particular, on T cells remain …

Abstract Annexin-A1 (Anx-A1) is an endogenous anti-inflammatory molecule and while
described as a repressor of innate immune responses, the role of Anx-A1 in adaptive …

The brain microenvironment is continuously monitored by microglia with the detection of
apoptotic cells or pathogens being rapidly followed by their phagocytosis to prevent …

Abstract Background Annexin A1 (ANXA1) and Translocator Protein-18KDa (TSPO) down-
regulate neuroinflammation. We investigated the role of recombinant ANXA1 (rANXA) on …

Blood–brain barrier (BBB) dysfunction is a fundamental cause of multiple sclerosis and
identifying the molecules that are responsible is an urgent matter. Protein expression was …

Abstract Objective. Annexin-1 (Anx-A1) has been recently shown to play a key role in T-cell
activation and to be highly expressed in T cells from RA patients. Here, we investigated the …

HIV-1 disease progression is paradoxically characterized by systemic chronic immune
activation and gut mucosal immune dysfunction, which is not fully defined. Annexin A1 …

Neutrophils (also named polymorphonuclear leukocytes or PMN) are essential components
of the immune system, rapidly recruited to sites of inflammation, providing the first line of …