Unexpected mechanism of biodegradation and defluorination of 2, 2-difluoro-1, 3-benzodioxole by Pseudomonas putida F1
Perfluorinated carbon atoms in a diether linkage are common in commercial anesthetics,
drugs, fungicides, and insecticides. An important chemical group comprising …
drugs, fungicides, and insecticides. An important chemical group comprising …
Nothing lasts forever: understanding microbial biodegradation of polyfluorinated compounds and perfluorinated alkyl substances
LP Wackett - Microbial biotechnology, 2022 - Wiley Online Library
Poly‐and perfluorinated chemicals, including perfluorinated alkyl substances (PFAS), are
pervasive in today's society, with a negative impact on human and ecosystem health …
pervasive in today's society, with a negative impact on human and ecosystem health …
Microwell Fluoride Screen for Chemical, Enzymatic, and Cellular Reactions Reveals Latent Microbial Defluorination Capacity for −CF3 Groups
The capacity to defluorinate polyfluorinated organic compounds is a rare phenotype in
microbes but is increasingly considered important for maintaining the environment. New …
microbes but is increasingly considered important for maintaining the environment. New …
Why is the biodegradation of polyfluorinated compounds so rare?
LP Wackett - Msphere, 2021 - Am Soc Microbiol
Thousands of heavily fluorinated chemicals are found in the environment, impact human
and ecosystem health, and are relatively resistant to biological and chemical degradation …
and ecosystem health, and are relatively resistant to biological and chemical degradation …
Structural insights into hydrolytic defluorination of difluoroacetate by microbial fluoroacetate dehalogenases
AN Khusnutdinova, KA Batyrova, G Brown… - The FEBS …, 2023 - Wiley Online Library
Fluorine forms the strongest single bond to carbon with the highest bond dissociation energy
among natural products. However, fluoroacetate dehalogenases (FADs) have been shown …
among natural products. However, fluoroacetate dehalogenases (FADs) have been shown …
[HTML][HTML] Engineering and characterization of dehalogenase enzymes from Delftia acidovorans in bioremediation of perfluorinated compounds
JD Harris, CM Coon, ME Doherty, EA McHugh… - Synthetic and Systems …, 2022 - Elsevier
Per-and Polyfluorinated alkyl substances (PFAS) are a broad class of synthetic compounds
that have fluorine substituted for hydrogen in several or all locations and are globally …
that have fluorine substituted for hydrogen in several or all locations and are globally …
Mapping the reaction coordinates of enzymatic defluorination
PWY Chan, AF Yakunin, EA Edwards… - Journal of the American …, 2011 - ACS Publications
The carbon− fluorine bond is the strongest covalent bond in organic chemistry, yet
fluoroacetate dehalogenases can readily hydrolyze this bond under mild physiological …
fluoroacetate dehalogenases can readily hydrolyze this bond under mild physiological …
[HTML][HTML] Microbial biodegradation of a novel fluorotelomer alcohol, 1H,1H,2H,2H,8H,8H-perfluorododecanol, yields short fluorinated acids
A Arakaki, Y Ishii, T Tokuhisa, S Murata, K Sato… - Applied microbiology …, 2010 - Springer
The accumulation of perfluorooctanoic acid (PFOA) has been detected in wildlife, soil, and
water. Further, 8: 2 fluorotelomer alcohol (8: 2 FTOH) is used for the industrial synthesis of …
water. Further, 8: 2 fluorotelomer alcohol (8: 2 FTOH) is used for the industrial synthesis of …
Biodefluorination and biotransformation of fluorotelomer alcohols by two alkane‐degrading Pseudomonas strains
MH Kim, N Wang, T McDonald… - Biotechnology and …, 2012 - Wiley Online Library
Abstract Fluorotelomer alcohols [FTOHs, F (CF2) nCH2CH2OH, n= 4, 6, and 8] are emerging
environmental contaminants. Biotransformation of FTOHs by mixed bacterial cultures has …
environmental contaminants. Biotransformation of FTOHs by mixed bacterial cultures has …
Characterization of a dibenzofuran-degrading strain of Pseudomonas aeruginosa, FA-HZ1
Dibenzofuran (DBF) derivatives have caused serious environmental problems, especially
those produced by paper pulp bleaching and incineration processes. Prominent for its …
those produced by paper pulp bleaching and incineration processes. Prominent for its …