Depression and HIV: a scoping review in search of neuroimmune biomarkers

A Mudra Rakshasa-Loots - Brain Communications, 2023 - academic.oup.com
People with HIV are at increased risk for depression, though the neurobiological
mechanisms underlying this are unclear. In the last decade, there has been a substantial …

Neuroinflammation in HIV-associated depression: Evidence and future perspectives

A Mudra Rakshasa-Loots, HC Whalley, JH Vera… - Molecular …, 2022 - nature.com
People living with HIV face a high risk of mental illness, especially depression. We do not yet
know the precise neurobiological mechanisms underlying HIV-associated depression …

[HTML][HTML] Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

AM Rakshasa-Loots, N Bakewell, DJ Sharp… - Translational …, 2023 - ncbi.nlm.nih.gov
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …

Biomarkers of central and peripheral inflammation mediate the association between HIV and depressive symptoms

A Mudra Rakshasa-Loots, N Bakewell, DJ Sharp… - Translational …, 2023 - nature.com
People living with HIV are at increased risk for depression, though the underlying
mechanisms for this are unclear. In the general population, depression is associated with …

Human immunodeficiency virus-associated depression: contributions of immuno-inflammatory, monoaminergic, neurodegenerative, and neurotrophic pathways

FB Del Guerra, JLI Fonseca, VM Figueiredo… - Journal of …, 2013 - Springer
In the era of greatly improved pharmacological treatment of HIV infection through highly
active antiretroviral therapy (HAART), HIV patients experience reduced viral loads, reduced …

Multi-modal analysis of inflammation as a potential mediator of depressive symptoms in young people with HIV: The GOLD depression study

A Mudra Rakshasa-Loots, S Naidoo, T Hamana… - Plos one, 2024 - journals.plos.org
People living with HIV are at three times greater risk for depressive symptoms. Inflammation
is a notable predictor of depression, and people with HIV exhibit chronic inflammation …

The comorbidity of depression and neurocognitive disorder in persons with HIV infection: call for investigation and treatment

K Goodkin, TH Evering, AM Anderson… - Frontiers in Cellular …, 2023 - frontiersin.org
Depression and neurocognitive disorder continue to be the major neuropsychiatric disorders
affecting persons with HIV (PWH). The prevalence of major depressive disorder is two to …

Molecular neuroimaging of inflammation in HIV

J Alagaratnam, A Winston - Clinical and experimental …, 2022 - academic.oup.com
People with HIV now have near-normal life expectancies due to the success of effective
combination antiretroviral therapy (cART). Following cART initiation, immune recovery …

[HTML][HTML] Sex-specific associations between plasma interleukin-6 and depression in persons with and without HIV

KJ Petersen, X Yu, MC Masters, JD Lobo, T Lu… - Brain, Behavior, & …, 2023 - Elsevier
Abstract Background Persons with HIV (PWH) have both more frequent depression and
higher levels of plasma inflammatory biomarkers compared to persons without HIV (PWoH) …

Immune activation and neuropsychiatric symptoms in HIV infection

EM Warriner, SB Rourke, BP Rourke… - The Journal of …, 2010 - Am Neuropsych Assoc
This study examined the role of biological processes in the development of specific
neuropsychiatric complications in HAART-naive adults with HIV/AIDS. Depressive symptoms …