Platelets in inflammation and immune modulations: functions beyond hemostasis
Platelets play central roles for maintaining the homeostasis of the blood coagulation. As they
are also involved in immune responses and host defenses, increasing evidences have …
are also involved in immune responses and host defenses, increasing evidences have …
Platelets and innate immunity
JW Semple, J Freedman - Cellular and Molecular Life Sciences, 2010 - Springer
Although platelets are best known as primary mediators of hemostasis, this function
intimately associates them with inflammatory processes, and it has been increasingly …
intimately associates them with inflammatory processes, and it has been increasingly …
Platelet activation: the mechanisms and potential biomarkers
SH Yun, EH Sim, RY Goh, JI Park… - BioMed research …, 2016 - Wiley Online Library
Beyond hemostasis and thrombosis, an increasing number of studies indicate that platelets
play an integral role in intercellular communication, mediating inflammatory and …
play an integral role in intercellular communication, mediating inflammatory and …
Platelet-neutrophil-interactions: linking hemostasis and inflammation
A Zarbock, RK Polanowska-Grabowska, K Ley - Blood reviews, 2007 - Elsevier
Platelets are essential for primary hemostasis, but they also play an important pro-
inflammatory role. Platelets normally circulate in a quiescent state. Upon activation, platelets …
inflammatory role. Platelets normally circulate in a quiescent state. Upon activation, platelets …
The era of thromboinflammation: platelets are dynamic sensors and effector cells during infectious diseases
L Guo, MT Rondina - Frontiers in immunology, 2019 - frontiersin.org
Platelets are anucleate cells produced by megakaryocytes. In recent years, a robust body of
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
literature supports the evolving role of platelets as key sentinel and effector cells in infectious …
Emerging roles for platelets as immune and inflammatory cells
CN Morrell, AA Aggrey, LM Chapman… - Blood, The Journal of …, 2014 - ashpublications.org
Despite their small size and anucleate status, platelets have diverse roles in vascular
biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also …
biology. Not only are platelets the cellular mediator of thrombosis, but platelets are also …
Platelets: emerging facilitators of cellular crosstalk in rheumatoid arthritis
O Olumuyiwa-Akeredolu, MJ Page, P Soma… - Nature Reviews …, 2019 - nature.com
Rheumatoid arthritis (RA) is an autoimmune disease in which a variety of circulating pro-
inflammatory cells and dysregulated molecules are involved in disease aetiology and …
inflammatory cells and dysregulated molecules are involved in disease aetiology and …
Platelets and their microparticles as key players in pathophysiological responses
D Varon, E Shai - Journal of Thrombosis and Haemostasis, 2015 - Wiley Online Library
Platelets are known to play a central role in primary hemostasis as well as in the
pathophysiology of thrombotic disorders. However, in addition to hemostasis, platelets are …
pathophysiology of thrombotic disorders. However, in addition to hemostasis, platelets are …
Platelet “first responders” in wound response, cancer, and metastasis
DG Menter, S Kopetz, E Hawk, AK Sood… - Cancer and Metastasis …, 2017 - Springer
Platelets serve as “first responders” during normal wounding and homeostasis. Arising from
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …
bone marrow stem cell lineage megakaryocytes, anucleate platelets can influence …