Platelets play a central role in primary hemostasis by forming aggregates that plug holes in
injured vessels. Half a century ago, detailed studies of the microvasculature by electron …

Platelets are central players in thrombosis and hemostasis but are increasingly recognized
as key components of the immune system. They shape ensuing immune responses by …

In addition to their well-known role as the cellular mediator of thrombosis, numerous studies
have identified key roles for platelets during various disease processes. Importantly …

This review collects evidence about immune and inflammatory functions of platelets from a
clinician's point of view. A focus on clinically relevant immune functions aims at stimulating …

Platelets display a number of properties besides the crucial function of repairing damaged
vascular endothelium and stopping bleeding; these are exploited to benefit patients …

Inflammation is an underlying feature of a variety of human diseases. An important
manifestation of this pathophysiological response is microvascular dysfunction, which …

Platelets are classically known as essential mediators of hemostasis and thrombosis.
However, in recent years, platelets have gained recognition for their inflammatory functions …

Despite the fact that the relationship between platelets and the inflammatory and immune
responses has been reviewed previously, the allocation of platelets among the inflammatory …

Platelets are conventionally defined as playing a vital role in homeostasis and thrombosis.
This role has over the years transformed as knowledge regarding platelets has expanded to …

Neutrophils are well known for their role in infection and inflammatory disease and are first
responders at sites of infection or injury. Platelets have an established role in hemostasis …