Association of ARNT splice variants with estrogen receptor-negative breast cancer, poor induction of vascular endothelial growth factor under hypoxia, and poor …
C Qin, C Wilson, C Blancher, M Taylor, S Safe… - Clinical cancer …, 2001 - AACR
The aryl hydrocarbon receptor nuclear translocator (ARNT) is a basic helix-loop-helix
transcription factor that forms heterodimers with the aryl hydrocarbon receptor (AhR) or …
transcription factor that forms heterodimers with the aryl hydrocarbon receptor (AhR) or …
Aryl hydrocarbon (Ah) nonresponsiveness in estrogen receptor-negative MDA-MB-231 cells is associated with expression of a variant arnt protein
CL Wilson, J Thomsen, DJ Hoivik, MT Wormke… - Archives of biochemistry …, 1997 - Elsevier
Several studies have reported a correlation between expression of the estrogen receptor
(ER) and aryl hydrocarbon (Ah) responsiveness in human breast cancer cell lines. MDA-MB …
(ER) and aryl hydrocarbon (Ah) responsiveness in human breast cancer cell lines. MDA-MB …
The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment
M Mandl, MK Lieberum, J Dunst, R Depping - Radiation Oncology, 2015 - Springer
Background Tumour hypoxia promotes radioresistance and is associated with poor
prognosis. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) …
prognosis. The transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) …
A truncated Ah receptor blocks the hypoxia and estrogen receptor signaling pathways: a viable approach for breast cancer treatment
KA Jensen, TC Luu, WK Chan - Molecular pharmaceutics, 2006 - ACS Publications
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor which requires
heterodimerization with the Ah receptor nuclear translocator (Arnt) for function. Arnt is also a …
heterodimerization with the Ah receptor nuclear translocator (Arnt) for function. Arnt is also a …
Suppression of the hypoxia inducible factor-1 function by redistributing the aryl hydrocarbon receptor nuclear translocator from nucleus to cytoplasm
The aryl hydrocarbon receptor nuclear translocator (ARNT) heterodimerizes with hypoxia
inducible factor-1α (HIF-1α), followed by upregulation of genes that are essential for …
inducible factor-1α (HIF-1α), followed by upregulation of genes that are essential for …
Identifying target genes of the aryl hydrocarbon receptor nuclear translocator (Arnt) using DNA microarray analysis
F Wang, S Shi, R Zhang, O Hankinson - 2006 - degruyter.com
The aryl hydrocarbon receptor nuclear translocator (Arnt) is a basic helix-loop-helix (bHLH)
protein that also contains a Per-Arnt-Sim (PAS) domain. In addition to forming heterodimers …
protein that also contains a Per-Arnt-Sim (PAS) domain. In addition to forming heterodimers …
Non-hypoxic transcriptional activation of the aryl hydrocarbon receptor nuclear translocator in concert with a novel hypoxia-inducible factor-1alpha isoform
KH Lee, JW Park, YS Chun - Nucleic acids research, 2004 - academic.oup.com
Aryl hydrocarbon receptor nuclear translocator (ARNT) belongs to the basic helix–loop–
helix Per-Arnt-Sim (bHLH PAS) protein which dimerizes with other PAS proteins. Although it …
helix Per-Arnt-Sim (bHLH PAS) protein which dimerizes with other PAS proteins. Although it …
Identification of differentially expressed three novel transcript variants of mouse ARNT gene
The aryl hydrocarbon receptor nuclear translocator (ARNT/HIF1‐β) is an obligatory
transcriptional partner of the aryl hydrocarbon receptor (AHR) and hypoxia‐inducible factor …
transcriptional partner of the aryl hydrocarbon receptor (AHR) and hypoxia‐inducible factor …
A molecular mechanism to switch the aryl hydrocarbon receptor from a transcription factor to an E3 ubiquitin ligase
S Luecke-Johansson, M Gralla… - … and cellular biology, 2017 - Am Soc Microbiol
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is known
as a mediator of toxic responses. Recently, it was shown that the AhR has dual functions …
as a mediator of toxic responses. Recently, it was shown that the AhR has dual functions …
ARNT is a potential direct HIF-1 target gene in human Hep3B hepatocellular carcinoma cells
M Mandl, R Depping - Cancer Cell International, 2017 - Springer
Background The transcription factor aryl hydrocarbon receptor nuclear translocator (ARNT)
participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular …
participates in the hypoxia-inducible factor (HIF) pathway which senses a decline in cellular …