Whether for constructing advanced materials and complex biological devices or for building
sophisticated coordination complexes with diverse metal-based functions, proteins are …

Metal-chelating heteroaryl small molecules have found widespread use as building blocks
for coordination-driven, self-assembling nanostructures. The metal-chelating noncanonical …

Owing to their central roles in cellular signaling, construction, and biochemistry, protein–
protein interactions (PPIs) and protein self-assembly have become a major focus of …

Through their unique and specific interactions with various metal ions, naturally occurring
proteins control structures and functions of many biological processes and functions in …

Advances in protein chemistry and molecular and structural biology have empowered
modern chemists to build complex biological architectures using a “first principles” …

Obtaining three-dimensional (3D) protein and peptide crystals on demand requires a
precisely orchestrated hierarchical assembly of biopolymer building blocks. In this work, we …

The evolution of proteins from simpler, self-assembled peptides provides a powerful
blueprint for the design of complex synthetic materials. Previously, peptide–metal …

We previously devised a strategy (metal-directed protein self-assembly, MDPSA) that utilizes
the simultaneous stability, lability, and directionality of metal− ligand bonds to drive protein …

Proteins are versatile macromolecules that can perform a variety of functions. In the past
three decades, they have been commonly used as building blocks to generate a range of …

In nature, proteins are the machinery that accomplish many functions through their specific
recognition and interactions in biological systems from single-celled to multicellular …