Distinct and redundant roles of exonucleases in Cryptococcus neoformans: Implications for virulence and mating

C Wollschlaeger, N Trevijano-Contador, X Wang… - Fungal Genetics and …, 2014 - Elsevier
Opportunistic pathogens like Cryptococcus neoformans are constantly exposed to changing
environments, in their natural habitat as well as when encountering a human host. This …

Cryptococcus neoformans: sex, morphogenesis, and virulence

Y Zhao, X Lin - Infection, Genetics and Evolution, 2021 - Elsevier
Cryptococcus neoformans is a dimorphic fungus that causes lethal meningoencephalitis
mainly in immunocompromised individuals. Different morphotypes enable this …

Introns Regulate Gene Expression in Cryptococcus neoformans in a Pab2p Dependent Pathway

C Goebels, A Thonn, S Gonzalez-Hilarion… - PLoS …, 2013 - journals.plos.org
Most Cryptococccus neoformans genes are interrupted by introns, and alternative splicing
occurs very often. In this study, we examined the influence of introns on C. neoformans gene …

Life Cycle of Cryptococcus neoformans

Y Zhao, J Lin, Y Fan, X Lin - Annual review of microbiology, 2019 - annualreviews.org
Cryptococcus neoformans is a ubiquitous environmental fungus and an opportunistic
pathogen that causes fatal cryptococcal meningitis. Advances in genomics, genetics, and …

Phenotypic characterization of HAM1, a novel mating regulator of the fungal pathogen Cryptococcus neoformans

E Arsenault Yee, RL Ross… - Microbiology …, 2024 - Am Soc Microbiol
Cryptococcus neoformans is a fungal pathogen responsible for> 200,000 yearly cases with
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …

DNA Mutations Mediate Microevolution between Host-Adapted Forms of the Pathogenic Fungus Cryptococcus neoformans

DA Magditch, TB Liu, C Xue, A Idnurm - 2012 - journals.plos.org
The disease cryptococcosis, caused by the fungus Cryptococcus neoformans, is acquired
directly from environmental exposure rather than transmitted person-to-person. One …

The Cys2His2 zinc finger protein Zfp1 regulates sexual reproduction and virulence in Cryptococcus neoformans

CL Fan, LT Han, ST Jiang, AN Chang, ZY Zhou… - Fungal genetics and …, 2019 - Elsevier
Cryptococcus neoformans is a ubiquitous yeast pathogen that often infects the human
central nervous system (CNS) to cause meningitis in immunocompromised individuals …

Going green in Cryptococcus neoformans: the recycling of a selectable drug marker

RD Patel, JK Lodge, LG Baker - Fungal Genetics and Biology, 2010 - Elsevier
Cryptococcus neoformans is an opportunistic fungal pathogen that primarily affects
immunocompromised individuals. Reverse genetics is commonly used to identify and …

An intergenic “safe haven” region in Cryptococcus neoformans serotype D genomes

Y Fan, X Lin - Fungal Genetics and Biology, 2020 - Elsevier
Cryptococcus neoformans is an opportunistic human fungal pathogen and serves as a
model organism for studies of eukaryotic microbiology and microbial pathogenesis. C …

The lncRNA RZE1 Controls Cryptococcal Morphological Transition

N Chacko, Y Zhao, E Yang, L Wang, JJ Cai, X Lin - PLoS genetics, 2015 - journals.plos.org
In the fungal pathogen Cryptococcus neoformans, the switch from yeast to hypha is an
important morphological process preceding the meiotic events during sexual development …