Transcriptional control of sexual development in Cryptococcus neoformans

ME Mead, CM Hull - Journal of Microbiology, 2016 - Springer
Developmental processes are essential for the normal life cycles of many pathogenic fungi,
and they can facilitate survival in challenging environments, including the human host …

Genetics of Cryptococcus neoformans

CM Hull, J Heitman - Annual review of genetics, 2002 - annualreviews.org
▪ Abstract Cryptococcus neoformans is a pathogenic fungus that primarily afflicts
immunocompromised patients, infecting the central nervous system to cause …

[HTML][HTML] Transcription Factors Mat2 and Znf2 Operate Cellular Circuits Orchestrating Opposite- and Same-Sex Mating in Cryptococcus neoformans

X Lin, JC Jackson, M Feretzaki, C Xue, J Heitman - PLoS genetics, 2010 - journals.plos.org
Cryptococcus neoformans is a human fungal pathogen that undergoes a dimorphic
transition from a unicellular yeast to multicellular hyphae during opposite sex (mating) and …

[HTML][HTML] Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to …

G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

[HTML][HTML] The Role of Oxidoreductase-Like Protein Olp1 in Sexual Reproduction and Virulence of Cryptococcus neoformans

QK Yu, LT Han, YJ Wu, TB Liu - Microorganisms, 2020 - mdpi.com
Cryptococcus neoformans is a basidiomycete human fungal pathogen causing lethal
meningoencephalitis, mainly in immunocompromised patients. Oxidoreductases are a class …

Characterizing the role of RNA silencing components in Cryptococcus neoformans

G Janbon, S Maeng, DH Yang, YJ Ko, KW Jung… - Fungal Genetics and …, 2010 - Elsevier
The RNA interference (RNAi) mediated by homology-dependent degradation of the target
mRNA with small RNA molecules plays a key role in controlling transcription and translation …

Multiple Gene Deletion in Cryptococcus neoformans Using the Cre–lox System

LG Baker, JK Lodge - Host-Fungus Interactions: Methods and Protocols, 2012 - Springer
Reverse genetics is commonly used to identify and characterize genes involved in a variety
of cellular processes. There is a limited set of positive selectable markers available for use in …

[HTML][HTML] The Temperature-Sensitive Role of Cryptococcus neoformans ROM2 in Cell Morphogenesis

BB Fuchs, RJ Tang, E Mylonakis - PloS one, 2007 - journals.plos.org
ROM2 is associated with Cryptococcus neoformans virulence. We examined additional roles
of ROM2 in C. neoformans and found that ROM2 plays a role in several cell functions …

Caught red feathered: infection from cockatoo to human and mice reveals genetic plasticity of Cryptococcus neoformans during mammalian passage

DG Cohen, RA Wingert - Tissue Barriers, 2024 - Taylor & Francis
The fungus Cryptococcus neoformans is pervasive in our environment and causes the
infectious disease cryptococcosis in humans, most commonly in immunocompromised …

Cryptococcus neoformans histone acetyltransferase Gcn5 regulates fungal adaptation to the host

TR O'Meara, C Hay, MS Price, S Giles… - Eukaryotic cell, 2010 - Am Soc Microbiol
Cryptococcus neoformans is an environmental fungus and an opportunistic human
pathogen. Previous studies have demonstrated major alterations in its transcriptional profile …