Cryptococcus neoformans Gene Expression during Murine Macrophage Infection
The fungal pathogen Cryptococcus neoformans survives phagocytosis by macrophages and
proliferates within, ultimately establishing latent infection as a facultative intracellular …
proliferates within, ultimately establishing latent infection as a facultative intracellular …
[HTML][HTML] The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection
GJC Freitas, L Gouveia-Eufrasio, ECP Emidio… - Cells, 2022 - mdpi.com
The phenotypic plasticity of Cryptococcus neoformans is widely studied and demonstrated in
vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the …
vitro, but its influence on pathogenicity remains unclear. In this study, we investigated the …
Morphology and its underlying genetic regulation impact the interaction between Cryptococcus neoformans and its hosts
Cryptococcus neoformans is a fungus that causes the majority of fatal cryptococcal
meningitis cases worldwide. This pathogen is capable of assuming different morphotypes …
meningitis cases worldwide. This pathogen is capable of assuming different morphotypes …
[HTML][HTML] PRM1 and KAR5 function in cell-cell fusion and karyogamy to drive distinct bisexual and unisexual cycles in the Cryptococcus pathogenic species complex
Sexual reproduction is critical for successful evolution of eukaryotic organisms in adaptation
to changing environments. In the opportunistic human fungal pathogens, the Cryptococcus …
to changing environments. In the opportunistic human fungal pathogens, the Cryptococcus …
[HTML][HTML] Cryptococcus neoformans Mediator Protein Ssn8 Negatively Regulates Diverse Physiological Processes and Is Required for Virulence
LI Wang, YS Lin, KH Liu, AY Jong, WC Shen - PLoS One, 2011 - journals.plos.org
Cryptococcus neoformans is a ubiquitously distributed human pathogen. It is also a model
system for studying fungal virulence, physiology and differentiation. Light is known to inhibit …
system for studying fungal virulence, physiology and differentiation. Light is known to inhibit …
A MAP kinase cascade composed of cell type specific and non‐specific elements controls mating and differentiation of the fungal pathogen Cryptococcus neoformans
RC Davidson, CB Nichols, GM Cox… - Molecular …, 2003 - Wiley Online Library
Cryptococcus neoformans is an opportunistic fungal pathogen with a defined sexual cycle in
which the α allele of the mating type locus is linked to virulence and haploid differentiation …
which the α allele of the mating type locus is linked to virulence and haploid differentiation …
[HTML][HTML] Phenotypic characterization of HAM1, a novel mating regulator of the fungal pathogen Cryptococcus neoformans
EA Yee, RL Ross, FH Santiago-Tirado - bioRxiv, 2024 - ncbi.nlm.nih.gov
Cryptococcus neoformans is a fungal pathogen responsible for> 200,000 yearly cases with
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …
a mortality as high as 81%. This burden results, in part, from an incomplete understanding of …
Intersection of fungal fitness and virulence in Cryptococcus neoformans
JC Panepinto, PR Williamson - FEMS yeast research, 2006 - academic.oup.com
The use of insertional mutagenesis to discover genes that impact laccase activity has
resulted in the identification of multiple cellular processes that affect the fitness of …
resulted in the identification of multiple cellular processes that affect the fitness of …
The Ess1 prolyl isomerase is dispensable for growth but required for virulence in Cryptococcus neoformans
P Ren, A Rossettini, V Chaturvedi… - Microbiology, 2005 - microbiologyresearch.org
Cryptococcus neoformans is an important human fungal pathogen that also serves as a
model for studies of fungal pathogenesis. C. neoformans contains several genes encoding …
model for studies of fungal pathogenesis. C. neoformans contains several genes encoding …
The interplay of phenotype and genotype in Cryptococcus neoformans disease
S Altamirano, KM Jackson, K Nielsen - Bioscience Reports, 2020 - portlandpress.com
Cryptococcus neoformans is an opportunistic fungal pathogen that causes life-threatening
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …
meningitis primarily in immunocompromised individuals. In order to survive and proliferate …