Hybridization has resulted in the origin and variation in extant species, and hybrids continue
to arise despite pre-and post-zygotic barriers that limit their formation and evolutionary …

Cryptococcus neoformans is a basidiomycete fungal pathogen of humans that has diverged
considerably from other model fungi such as Neurospora crassa, Aspergillus nidulans …

Proliferation and host evasion are critical processes to understand at a basic biological level
for improving infectious disease treatment options. The human fungal pathogen …

Cryptococcus neoformans is an opportunistic yeast-like pathogen that mainly infects
immunocompromised individuals and causes fatal meningitis. Sexual reproduction can …

This chapter discusses the ability of the pathogenic cryptococci to proliferate intracellularly
and examines the different strategies cryptococci use to exit host cells. The intracellular …

The study of quantitative traits provides a window on the interactions between multiple
unlinked genetic loci. The interaction between hosts and pathogenic microbes, such as …

Genome copy number variation occurs during each mitotic and meiotic cycle and it is crucial
for organisms to maintain their natural ploidy. Defects in ploidy transitions can lead to …

Cryptococcus neoformans (Cn), the major causative agent of human fungal
meningoencephalitis, replicates within phagolysosomes of infected host cells. Despite more …

This chapter presents Cryptococcus neoformans, an important model human fungal
pathogen, with a focus on sexual reproduction and morphogenesis given that they play key …

Cryptococcosis is a severe fungal disease causing 220,000 cases of cryptococcal meningitis
yearly. The etiological agents of cryptococcosis are taxonomically grouped into at least two …