Discovery and verification of urinary peptides in type 2 diabetes mellitus with kidney injury
G Fu, Y Du, L Chu, M Zhang - Experimental Biology and …, 2016 - journals.sagepub.com
Varying degrees of renal injury could lead to different changes in urinary protein
composition. We want to find urinary candidate peptide biomarkers in type 2 diabetic …
composition. We want to find urinary candidate peptide biomarkers in type 2 diabetic …
[HTML][HTML] Two urinary peptides associated closely with type 2 diabetes mellitus
M Zhang, G Fu, T Lei - PloS one, 2015 - journals.plos.org
Objective To monitor of type 2 diabetes more simply, conveniently and noninvasively, we are
trying to identify the potential urinary peptides that associated with different stages of …
trying to identify the potential urinary peptides that associated with different stages of …
Identification of urinary biomarkers for type 2 diabetes using bead-based proteomic approach
L Chu, G Fu, Q Meng, H Zhou, M Zhang - Diabetes Research and Clinical …, 2013 - Elsevier
Aims To seek urinary peptides as biomarkers distinguishing type 2 diabetes mellitus (T2DM)
patients from healthy controls. Methods Random urine samples obtained from 28 patients …
patients from healthy controls. Methods Random urine samples obtained from 28 patients …
[HTML][HTML] Identification of urinary proteins potentially associated with diabetic kidney disease
RK Marikanty, MK Gupta… - Indian journal of …, 2016 - journals.lww.com
Diabetic nephropathy (DN) is the most common cause of chronic kidney disease. Although
several parameters are used to evaluate renal damage, in many instances, there is no …
several parameters are used to evaluate renal damage, in many instances, there is no …
[HTML][HTML] Urinary peptidomic analysis identifies potential biomarkers for acute rejection of renal transplantation
TK Sigdel, XB Ling, KH Lau, L Li, J Schilling… - Clinical Proteomics, 2009 - Springer
Introduction Human urine is a complex matrix of proteins, endogenous peptides, lipids, and
metabolites. The level of any or all of these components can reflect the pathophysiological …
metabolites. The level of any or all of these components can reflect the pathophysiological …
[HTML][HTML] Urinary peptidomics and bioinformatics for the detection of diabetic kidney disease
LA Brondani, AA Soares, M Recamonde-Mendoza… - Scientific reports, 2020 - nature.com
The aim of this study was to establish a peptidomic profile based on LC-MS/MS and random
forest (RF) algorithm to distinguish the urinary peptidomic scenario of type 2 diabetes …
forest (RF) algorithm to distinguish the urinary peptidomic scenario of type 2 diabetes …
[HTML][HTML] Urinary peptidomic biomarkers in kidney diseases
V Sirolli, L Pieroni, L Di Liberato, A Urbani… - International journal of …, 2019 - mdpi.com
In order to effectively develop personalized medicine for kidney diseases we urgently need
to develop highly accurate biomarkers for use in the clinic, since current biomarkers of …
to develop highly accurate biomarkers for use in the clinic, since current biomarkers of …
Urinary proteins detected using modern proteomics intervene in early type 2 diabetic kidney disease–a pilot study
A Golea-Secara, C Munteanu, M Sarbu… - Biomarkers in …, 2020 - Taylor & Francis
Aim: An advanced proteomics platform for protein biomarker discovery in diabetic chronic
kidney disease (DKD) was developed, validated and implemented. Materials & methods …
kidney disease (DKD) was developed, validated and implemented. Materials & methods …
[HTML][HTML] Peptidomic analysis of urine from youths with early type 1 diabetes reveals novel bioactivity of uromodulin peptides in vitro
JAD Van, S Clotet-Freixas, J Zhou, I Batruch… - Molecular & Cellular …, 2020 - ASBMB
Chronic hyperglycemia is known to disrupt the proteolytic milieu, initiating compensatory
and maladaptive pathways in the diabetic kidney. Such changes in intrarenal proteolysis are …
and maladaptive pathways in the diabetic kidney. Such changes in intrarenal proteolysis are …
Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria
ML Merchant, BA Perkins, GM Boratyn… - Journal of the …, 2009 - journals.lww.com
One third of patients with type 1 diabetes and microalbuminuria experience an early,
progressive decline in renal function that leads to advanced stages of chronic kidney …
progressive decline in renal function that leads to advanced stages of chronic kidney …
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