Do proton pump inhibitors attenuate the effect of aspirin on platelet aggregation? A randomized crossover study

AB Adamopoulos, GN Sakizlis… - Journal of …, 2009 - journals.lww.com
It is common practice to coadminister proton pump inhibitors with aspirin to diminish the risk
of upper gastrointestinal bleeding. This is the first study that investigated the potential impact …

Incidence of gastrointestinal bleeding in patients with cardiovascular disease: buffered aspirin versus enteric-coated aspirin

Y Hirata, H Kataoka, T Shimura… - scandinavian Journal …, 2011 - Taylor & Francis
Objective. Aspirin-induced enteropathy is increasing, but whether the type of aspirin affects
the gastrointestinal (GI) bleeding, especially small intestine, is unclear. The incidence of GI …

[PDF][PDF] The prevalence of gastroduodenal mucosal injuries in aspirin users

T Thongbai - J Med Assoc Thai, 2013 - thaiscience.info
Background: Aspirin is a widely used medication for primary and secondary prevention of
cardiovascular and cerebrovascular events. The gastrointestinal risks of aspirin are well …

Effect of egualen sodium hydrate on small-intestinal mucosal damage induced by low-dose aspirin: a prospective randomized clinical trial

M Iguchi, K Kakimoto, T Kuramoto… - Journal of clinical …, 2018 - jstage.jst.go.jp
抄録 Low-dose aspirin, which is widely used to reduce the risk of cardio-and
cerebrovascular thrombosis, often induces gastroenteropathy by increasing the permeability …

Upper gastrointestinal complications induced by anti-platelet agents

T Kawai, H Sugimoto, M Fukuzawa… - Clinical journal of …, 2013 - Springer
Low-dose aspirin and thienopyridine are associated with gastrointestinal (GI) complications
such as petechiae, erosion, ulcer, bleeding, and perforation. The incidence of GI bleeding in …

[PDF][PDF] Does Low Dose Aspirin Increase Gastrointestinal Bleeding?

KN Shim - The Korean Journal of Gastroenterology, 2012 - synapse.koreamed.org
이 연구는 저용량의 acetylsalicylic acid (아스피린; 75-325 mg) 을 단독 또는 병합으로
투여받은 환자에서 총 사망과 출혈 (특히 위장관 출혈) 의 위험도를 평가하기 위하여 시행된 …

Clinical study of upper gastrointestinal bleeding associated with low-dose aspirin in Japanese patients.

K Okada, M Inamori, K Imajo, H Chiba… - Hepato …, 2009 - europepmc.org
Results The occurrence rate of UGIB was 0.209 UGIB per 100 patient-years at least. The
multivariate odds ratio of LDA-associated UGIB was 3.318 (95% confidence interval (CI) …

[HTML][HTML] The protective effect of teprenone on aspirin-related gastric mucosal injuries

J Zhao, Y Fan, W Ye, W Feng, Y Hu, L Cai… - … Research and Practice, 2019 - hindawi.com
Objective. Aspirin usage is associated with increased risk of gastrointestinal bleeding. The
present study explored the potential of teprenone, an antiulcerative, in preventing aspirin …

Comparison of teprenone and famotidine against gastroduodenal mucosal damage in patients taking low‐dose aspirin

T Takeuchi, K Ota, S Harada, Y Kojima… - Journal of …, 2014 - Wiley Online Library
Abstract Background and Aim Proton‐pump inhibitors are known to be effective in the
treatment and prevention of ulcers related to low‐dose aspirin (LDA), but few reports …

The effects of nonsteroidal anti-inflammatory drugs on platelet function and severity of upper gastrointestinal haemorrhage

S Pasa, K Bayan, M Kucukoner, Y Tuzun… - Journal of thrombosis …, 2009 - Springer
Nonsteroidal anti-inflammatory drugs (NSAIDs) cause gastrointestinal (GI) damage primarily
due to the inhibition of prostaglandin synthesis in gastric mucosa, which is an important …