TRPM2: a calcium influx pathway regulated by oxidative stress and the novel second messenger ADP-ribose
FJP Kühn, I Heiner, A Lückhoff - Pflügers Archiv, 2005 - Springer
A unique functional property within the transient receptor potential (TRP) family of cation
channels is the gating of TRP (melastatin) 2 (TRPM2) channels by ADP-ribose (ADPR) …
channels is the gating of TRP (melastatin) 2 (TRPM2) channels by ADP-ribose (ADPR) …
TRPM2 cation channels, oxidative stress and neurological diseases: where are we now?
M Nazıroğlu - Neurochemical research, 2011 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential 2
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …
(TRPM2) channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ or by …
Identification of direct and indirect effectors of the transient receptor potential melastatin 2 (TRPM2) cation channel
B Tóth, L Csanády - Journal of Biological Chemistry, 2010 - ASBMB
Transient receptor potential melastatin 2 (TRPM2) is a Ca 2+-permeable cation channel
involved in physiological and pathophysiological processes linked to oxidative stress …
involved in physiological and pathophysiological processes linked to oxidative stress …
TRPM2: a multifunctional ion channel for calcium signalling
A Sumoza‐Toledo, R Penner - The Journal of physiology, 2011 - Wiley Online Library
The transient potential receptor melastatin‐2 (TRPM2) channel has emerged as an
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
important Ca2+ signalling mechanism in a variety of cells, contributing to cellular functions …
TRPM2 protects against tissue damage following oxidative stress and ischaemia–reperfusion
BA Miller, JY Cheung - The Journal of physiology, 2016 - Wiley Online Library
TRPM channels are a subgroup of the transient receptor potential (TRP) channel
superfamily whose members have important roles in cell proliferation and survival. TRPM2 …
superfamily whose members have important roles in cell proliferation and survival. TRPM2 …
Intracellular calcium activates TRPM2 and its alternative spliced isoforms
Melastatin-related transient receptor potential channel 2 (TRPM2) is a Ca2+-permeable,
nonselective cation channel that is involved in oxidative stress-induced cell death and …
nonselective cation channel that is involved in oxidative stress-induced cell death and …
The role of TRP channels in oxidative stress-induced cell death
BA Miller - The Journal of membrane biology, 2006 - Springer
The transient receptor potential (TRP) protein superfamily is a diverse group of voltage-
independent calcium-permeable cation channels expressed in mammalian cells. These …
independent calcium-permeable cation channels expressed in mammalian cells. These …
The calcium‐permeable non‐selective cation channel TRPM2 is modulated by cellular acidification
JG Starkus, A Fleig, R Penner - The Journal of physiology, 2010 - Wiley Online Library
TRPM2 is a calcium‐permeable non‐selective cation channel expressed in the plasma
membrane and in lysosomes that is critically involved in aggravating reactive oxygen …
membrane and in lysosomes that is critically involved in aggravating reactive oxygen …
New molecular mechanisms on the activation of TRPM2 channels by oxidative stress and ADP-ribose
M Nazıroğlu - Neurochemical research, 2007 - Springer
Abstract The Na+ and Ca 2+-permeable melastatin related transient receptor potential
(TRPM2) cation channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ …
(TRPM2) cation channels can be gated either by ADP-ribose (ADPR) in concert with Ca 2+ …
A calcium influx pathway regulated separately by oxidative stress and ADP-Ribose in TRPM2 channels: single channel events
M Nazıroğlu, A Lückhoff - Neurochemical research, 2008 - Springer
A melastatin-like transient receptor potential 2 (TRPM2) channel is activated in concert with
Ca 2+ by intracellular adenosine diphosphoribose (ADPR) binding to the channel's enzyme …
Ca 2+ by intracellular adenosine diphosphoribose (ADPR) binding to the channel's enzyme …