MSH3-deficiency initiates EMAST without oncogenic transformation of human colon epithelial cells
C Campregher, G Schmid, F Ferk, S Knasmüller… - PloS one, 2012 - journals.plos.org
Background/Aim Elevated microsatellite instability at selected tetranucleotide repeats
(EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been …
(EMAST) is a genetic signature in certain cases of sporadic colorectal cancer and has been …
Oxidative stress induces nuclear-to-cytosol shift of hMSH3, a potential mechanism for EMAST in colorectal cancer cells
SS Tseng-Rogenski, H Chung, MB Wilk, S Zhang… - PloS one, 2012 - journals.plos.org
Background Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST)
is a genetic signature observed in 60% of sporadic colorectal cancers (CRCs). Unlike …
is a genetic signature observed in 60% of sporadic colorectal cancers (CRCs). Unlike …
EMAST is a form of microsatellite instability that is initiated by inflammation and modulates colorectal cancer progression
JM Carethers, M Koi, SS Tseng-Rogenski - Genes, 2015 - mdpi.com
DNA mismatch repair (MMR) function is critical for correcting errors coincident with
polymerase-driven DNA replication, and its proteins are frequent targets for inactivation …
polymerase-driven DNA replication, and its proteins are frequent targets for inactivation …
[HTML][HTML] Elevated microsatellite alterations at selected tetranucleotides (EMAST) is not attributed to MSH3 loss in stage I-III colon cancer: an automated, digitalized …
INTRODUCTION: EMAST is a poorly understood form of microsatellite instability (MSI) in
colorectal cancer (CRC) for which loss of MSH3 has been proposed as the underlying …
colorectal cancer (CRC) for which loss of MSH3 has been proposed as the underlying …
Genetic instability caused by loss of MutS homologue 3 in human colorectal cancer
Microsatellite instability (MSI) is a hallmark of mismatch repair (MMR) deficiency. High levels
of MSI at mononucleotide and dinucleotide repeats in colorectal cancer (CRC) are attributed …
of MSI at mononucleotide and dinucleotide repeats in colorectal cancer (CRC) are attributed …
Aberrant protein expression and frequent allelic loss of MSH3 in colorectal cancer with low-level microsatellite instability
J Plaschke, M Preußler, A Ziegler… - International journal of …, 2012 - Springer
Purpose High level of microsatellite instability (MSI-H) in colorectal cancer (CRC) is caused
by the inactivation of mismatch repair (MMR) genes; however, it is unknown for tumors with …
by the inactivation of mismatch repair (MMR) genes; however, it is unknown for tumors with …
Relationship of EMAST and microsatellite instability among patients with rectal cancer
B Devaraj, A Lee, BL Cabrera, K Miyai, L Luo… - Journal of …, 2010 - Elsevier
Background Elevated microsatellite instability at selected tetranucleotide repeats (EMAST) is
a genetic signature identified in 60% of sporadic colon cancers and may be linked with …
a genetic signature identified in 60% of sporadic colon cancers and may be linked with …
Elevated microsatellite alterations at selected tetranucleotide repeats (EMAST) and microsatellite instability in patients with colorectal cancer and its clinical features
Purpose: Recently, a different type of microsatellite instability (MSI) instability designated
'elevated microsatellite alterations at selected tetranucleotide repeats'(EMAST) has been …
'elevated microsatellite alterations at selected tetranucleotide repeats'(EMAST) has been …
Microsatellite alterations at selected tetranucleotide repeats are associated with morphologies of colorectal neoplasias
SY Lee, H Chung, B Devaraj, M Iwaizumi, HS Han… - Gastroenterology, 2010 - Elsevier
BACKGROUND & AIMS:: Elevated microsatellite alterations at selected tetranucleotide
repeats (EMAST) occurs during microsatellite instability (MSI) that is not associated with …
repeats (EMAST) occurs during microsatellite instability (MSI) that is not associated with …
Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers
T Hienonen, H Sammalkorpi, S Enholm, P Alhopuro… - Cancer research, 2005 - AACR
DNA mismatch repair (MMR)–deficient cells typically accumulate mutations in short
repetitive DNA tracts. This microsatellite instability (MSI) facilitates malignant transformation …
repetitive DNA tracts. This microsatellite instability (MSI) facilitates malignant transformation …