Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin …
DJ Stumpo, NA Byrd, RS Phillips, S Ghosh… - … and cellular biology, 2004 - Am Soc Microbiol
The mouse gene Zfp36L1 encodes zinc finger protein 36-like 1 (Zfp36L1), a member of the
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
tristetraprolin (TTP) family of tandem CCCH finger proteins. TTP can bind to AU-rich …
Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts
WS Lai, JS Parker, SF Grissom, DJ Stumpo… - … and cellular biology, 2006 - Taylor & Francis
Tristetraprolin (TTP) is a tandem CCCH zinc finger protein that was identified through its
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
rapid induction by mitogens in fibroblasts. Studies of TTP-deficient mice and cells derived …
Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis
DJ Stumpo, HE Broxmeyer, T Ward… - Blood, The Journal …, 2009 - ashpublications.org
Members of the tristetraprolin family of tandem CCCH finger proteins can bind to AU-rich
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
elements in the 3′-untranslated region of mRNAs, leading to their deadenylation and …
Phylogenetic distribution and evolution of the linked RNA-binding and NOT1-binding domains in the tristetraprolin family of tandem CCCH zinc finger proteins
PJ Blackshear, L Perera - Journal of Interferon & Cytokine Research, 2014 - liebertpub.com
In humans, the tristetraprolin or TTP family of CCCH tandem zinc finger (TZF) proteins
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
comprises 3 members, encoded by the genes ZFP36, ZFP36L1, and ZFP36L2. These …
Comparative expression of tristetraprolin (TTP) family member transcripts in normal human tissues and cancer cell lines
DM Carrick, PJ Blackshear - Archives of biochemistry and biophysics, 2007 - Elsevier
The tristetraprolin (TTP) family of tandem zinc finger proteins comprises three members in
man and most other mammals, with a fourth expressed in rodents. In mice, gene disruption …
man and most other mammals, with a fourth expressed in rodents. In mice, gene disruption …
[HTML][HTML] Members of the tristetraprolin family of tandem CCCH zinc finger proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
RS Phillips, SBV Ramos, PJ Blackshear - Journal of Biological Chemistry, 2002 - ASBMB
Members of the tristetraprolin (TTP) family of CCCH tandem zinc finger proteins can bind
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
directly to certain types of AU-rich elements (AREs) in mRNA. Experiments in TTP-deficient …
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA
WS Lai, E Carballo, JR Strum… - … and cellular biology, 1999 - Am Soc Microbiol
Mice deficient in tristetraprolin (TTP), the prototype of a family of CCCH zinc finger proteins,
develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-α) …
develop an inflammatory syndrome mediated by excess tumor necrosis factor alpha (TNF-α) …
Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability
E Carballo, WS Lai… - Blood, The Journal of the …, 2000 - ashpublications.org
Deficiency of tristetraprolin (TTP), the prototype of the CCCH zinc finger proteins, results in a
complex inflammatory syndrome in mice. Most aspects of the syndrome are secondary to …
complex inflammatory syndrome in mice. Most aspects of the syndrome are secondary to …
[HTML][HTML] Tristetraprolin impairs NF-κB/p65 nuclear translocation
YM Schichl, U Resch, R Hofer-Warbinek… - Journal of Biological …, 2009 - ASBMB
Tristetraprolin (TTP) is a prototypic family member of CCCH-type tandem zinc-finger domain
proteins that regulate mRNA destabilization in eukaryotic cells. TTP binds to AU-rich …
proteins that regulate mRNA destabilization in eukaryotic cells. TTP binds to AU-rich …
Tristetraprolin regulates interleukin-6 expression through p38 MAPK-dependent affinity changes with mRNA 3′ untranslated region
Tristetraprolin (TTP) is a well-characterized, zinc finger-containing, RNA-binding protein.
TTP targets tumor necrosis factor α for degradation via the 3′ untranslated region (3 …
TTP targets tumor necrosis factor α for degradation via the 3′ untranslated region (3 …