Effect of early and focused benzodiazepine therapy on length of stay in severe alcohol withdrawal syndrome

JA Lee, JJ Duby, CS Cocanour - Clinical Toxicology, 2019 - Taylor & Francis
Objective: Current evidence supports symptom-triggered therapy for alcohol withdrawal
syndrome (AWS). Early, escalating therapy with benzodiazepines (BZD) appears to …

A symptom-triggered benzodiazepine protocol utilizing SAS and CIWA-Ar scoring for the treatment of alcohol withdrawal syndrome in the critically ill

S Sen, P Grgurich, A Tulolo… - Annals of …, 2017 - journals.sagepub.com
Background: There are limited data on the efficacy of symptom-triggered therapy for alcohol
withdrawal syndrome (AWS) in the intensive care unit (ICU). Objective: To evaluate the …

A comparison of injectable diazepam and lorazepam in the goal-directed management of severe alcohol withdrawal

KH Brickel, EK Hodge… - Annals of …, 2024 - journals.sagepub.com
Background: Benzodiazepines are the gold standard for treatment of alcohol withdrawal, yet
the selection of a preferred benzodiazepine is limited due to a lack of comparative studies …

Benzodiazepine treatment and hospital course of medical inpatients with alcohol withdrawal syndrome in the Veterans Health Administration

TL Steel, CA Malte, KA Bradley, EJ Hawkins - Mayo Clinic Proceedings …, 2022 - Elsevier
Objective To describe initial benzodiazepine dosing strategies and factors associated with
variation in benzodiazepine dosing in a national cohort of hospitalized patients with alcohol …

Alcohol withdrawal syndrome in critically ill patients: protocolized versus nonprotocolized management

JJ Duby, AJ Berry, P Ghayyem, MD Wilson… - Journal of Trauma …, 2014 - journals.lww.com
BACKGROUND Approximately 18% to 25% of patients with alcohol use disorders admitted
to the hospital develop alcohol withdrawal syndrome (AWS). Symptom-triggered dosing of …

The role of diazepam loading for the treatment of alcohol withdrawal syndrome in hospitalized patients

AJ Muzyk, JG Leung, S Nelson… - … American journal on …, 2013 - Wiley Online Library
Background Alcohol withdrawal accounts for a significant amount of hospital admissions
and can quickly progress to the development of delirium tremens (DTs), seizures, and death …

Treatment of alcohol withdrawal syndrome: phenobarbital vs CIWA-Ar protocol

WP Tidwell, TL Thomas, JD Pouliot, AE Canonico… - American Journal of …, 2018 - AACN
Background Benzodiazepine-based therapy for alcohol withdrawal is associated with
agitation and respiratory depression. Treatment can be complicated by a need for adjunctive …

The safety and utility of phenobarbital use for the treatment of severe alcohol withdrawal syndrome in the medical intensive care unit

M Oks, KL Cleven, L Healy, M Wei… - Journal of intensive …, 2020 - journals.sagepub.com
Background: Alcohol withdrawal syndrome (AWS) is a common reason for admission to a
medical intensive care unit (MICU) and requires significant hospital resource utilization …

[HTML][HTML] Phenobarbital versus lorazepam for management of alcohol withdrawal syndrome: a retrospective cohort study

F Hawa, L Gilbert, B Gilbert, V Hereford, A Hawa… - Cureus, 2021 - ncbi.nlm.nih.gov
Methods This is a retrospective cohort study over a two-year period (March, 2016 to March,
2018), conducted at three hospitals within the St. Joseph Mercy Health System. We included …

Implementation of an ICU‐specific alcohol withdrawal syndrome management protocol reduces the need for mechanical ventilation

JJ Heavner, KM Akgün, MS Heavner… - … : The Journal of …, 2018 - Wiley Online Library
Study Objective Alcohol use disorders are prevalent and put patients at risk for developing
alcohol withdrawal syndrome (AWS). Treatment of AWS with a symptom‐triggered protocol …