There is a large genetic diversity of Plasmodium falciparum strains that infect people
causing diverse malaria symptoms. This study was carried out to explore the effect of mixed …

Background Multiplicity and genetic diversity of Plasmodium falciparum infection might play
a role in determining the clinical outcome of malaria infection and could be a fair reflection of …

Abstract Background Genetic diversity in Plasmodium falciparum poses a major threat to
malaria control and elimination interventions. Characterization of the genetic diversity of P …

Background Plasmodium falciparum parasites are known to exhibit extensive genetic
diversity in areas of high transmission intensity and infected individuals in such communities …

Background Malaria remains a public health challenge in sub-Saharan Africa with
Plasmodium falciparum being the principal cause of malaria disease morbidity and mortality …

Background Malaria infection can present with a wide variety of symptoms, ranging from
mild to severe. Plasmodium falciparum isolates in uncomplicated and severe malaria …

Background The clinical presentation of malaria, considered as the result of a complex
interaction between parasite and human genetics, is described to be different between rural …

Objective To analyse the genetic diversity of Plasmodium falciparum (P. falciparum) using
msp-1 and msp-2 as antigenic markers. Methods Parasite DNA was extracted from 100 …

Background Genotyping malaria parasites to assess their diversity in different geographic
settings have become necessary for the selection of antigenic epitopes for vaccine …

Background The sickle-cell trait protects against severe Plasmodium falciparum malaria and
reduces susceptibility to mild malaria but does not prevent infection. The exact mechanism …