[HTML][HTML] The androgen receptor expression and association with patient's survival in different cancers

C Hu, D Fang, H Xu, Q Wang, H Xia - Genomics, 2020 - Elsevier
To understand the androgen receptor (AR) in different human malignancies, we conducted a
pan-cancer analysis of AR in different tumor tissues and association with patient survival …

[HTML][HTML] A protective role for androgen receptor in clear cell renal cell carcinoma based on mining TCGA data

H Zhao, JT Leppert, DM Peehl - PLoS One, 2016 - journals.plos.org
Androgen receptor (AR) is expressed in normal murine and human kidneys of both genders,
but its physiologic role is uncertain. Several studies showed loss of AR in renal cell …

[HTML][HTML] Androgen Receptor Activation in Glioblastoma Can Be Achieved by Ligand-Independent Signaling through EGFR—A Potential Therapeutic Target

N Zalcman, M Gutreiman, T Shahar, M Weller… - International Journal of …, 2021 - mdpi.com
Androgen receptor (AR) is a ligand-mediated transcription factor that belongs to the
superfamily of steroid receptors. AR is overexpressed in most glioblastomas and is a …

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

C Chang, SO Lee, S Yeh, TM Chang - Oncogene, 2014 - nature.com
The androgen receptor (AR) is expressed in many cell types and the androgen/AR signaling
has been found to have important roles in modulating tumorigenesis and metastasis in …

[HTML][HTML] Androgen regulation of the androgen receptor coregulators

A Urbanucci, KK Waltering, HE Suikki, MA Helenius… - BMC cancer, 2008 - Springer
Background The critical role of the androgen receptor (AR) in the development of prostate
cancer is well recognized. The transcriptional activity of AR is partly regulated by …

[HTML][HTML] A molecular analysis provides novel insights into androgen receptor signalling in breast cancer

J Mehta, S Asthana, CC Mandal, S Saxena - PloS one, 2015 - journals.plos.org
Background Androgen Receptor (AR) is an essential transcription factor for the development
of secondary sex characteristics, spermatogenesis and carcinogenesis. Recently AR has …

Expression of androgen receptor and its phosphorylated forms in breast cancer progression

Q Ren, L Zhang, R Ruoff, S Ha, J Wang, S Jain… - Cancer, 2013 - Wiley Online Library
BACKGROUND Androgen receptor (AR) expression in breast cancers may serve as a
prognostic and predictive marker. We examined the expression pattern of AR and its …

[PDF][PDF] Androgens and androgen receptor in prostate and ovarian malignancies

KL Meehan, MD Sadar - Front Biosci, 2003 - article.imrpress.com
Introduction 3. Androgen biosynthesis 3.1 Androgen biosynthesis in men 3.2. Androgen
biosynthesis in women 4. Risk associated with increased androgen levels in cancer 4.1 …

Identification of novel androgen response genes in prostate cancer cells by coupling chromatin immunoprecipitation and genomic microarray analysis

K Takayama, K Kaneshiro, S Tsutsumi, K Horie-Inoue… - Oncogene, 2007 - nature.com
The androgen receptor (AR) plays a key role as a transcriptional factor in prostate
development and carcinogenesis. Identification of androgen-regulated genes is essential to …

High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer …

R Li, T Wheeler, H Dai, A Frolov… - The American journal …, 2004 - journals.lww.com
Background: Prostate cancer (PCa) is androgen dependent and is regulated by
androgen/androgen receptor (AR) signaling pathway. However, the clinical significance of …