Candida species represent the main cause of opportunistic fungal infections worldwide, and
Candida albicans remains the most common etiological agent of candidiasis, now the third …

Candida albicans is the most common etiologic agent of systemic fungal infections with
unacceptably high mortality rates. The existing arsenal of antifungal drugs is very limited and …

Methods: To address the pressing need for new antifungals, we have performed a high-
content screen of 20,000 small molecules in a chemical library (NOVACore) to identify …

Candida albicans remains the main etiologic agent of candidiasis, the most common fungal
infection and now the third most frequent infection in US hospitals. The scarcity of antifungal …

The human fungal pathogen Candida albicans can form biofilms on biotic and abiotic
surfaces, which are inherently resistant to antifungal drugs. We screened the Chembridge …

Candida albicans remains the main causative agent of candidiasis, one of the most frequent
nosocomial infections, with unacceptably high mortality rates. Biofilm formation is a major …

Introduction: Targeting pathogenetic mechanisms, rather than essential processes,
represents a very attractive alternative for the development of new antibiotics. This may be …

Candida albicans is an opportunistic fungal pathogen, which causes a plethora of
superficial, as well as invasive, infections in humans. The ability of this fungus in switching …

We have previously identified a small molecule compound, N-[3-(allyloxy)-phenyl]-4-
methoxybenzamide (9029936), that exerts potent inhibitory activity against filamentation and …

Candida albicans is an opportunistic pathogen, typically found as a benign commensal
yeast living on skin and mucosa, but poised to invade injured tissue to cause local …