Sexual development and reproduction are largely linked to epigenetic changes in many fish
species. However, understanding of epigenetic regulation in scombrid species, such as …

DNA methylation-mediated transcriptional regulation has been considered to significantly
impact some steroidogenic enzyme genes expression. To uncover the roles of DNA …

The genes coding for Cytochrome P450 aromatase (cyp19a1a and cyp19a1b) and estrogen
(E 2) receptors (esr1, esr2a and esr2b) play a conserved role in ovarian differentiation and …

In vertebrates, the aromatase coded by the cyp19a1a gene can catalyze the conversion from
androgens to estrogens. Thus, the regulatory mechanisms of cyp19a1a gene expression are …

Tunas (genus Thunnus) are one of the most ecologically and commercially important fish
worldwide. To establish a biological basis for reproduction in this globally essential species …

Sex determination is a complex process that can be influenced by environment in various
taxa. Disturbed environments can affect population sex ratios and thus threaten their …

Background Protogynous fishes can change sex from female to male; concomitantly, their
ovarian tissue is completely replaced by testicular tissue. The high functional conservation of …

Exogenous oestrogen 17β-oestradiol (E2) has been shown to effectively induce feminization
in teleosts. However, the molecular mechanisms underlying the process remain unclear …

The sex ratio of olive flounder Paralichthys olivaceus is sensitive to temperature or
exogenous hormone exposures in the period of gonadal differentiation. Among sex-related …

Sex ratio shifts in response to temperature are common in fish and reptiles. However, the
mechanism linking temperature during early development and sex ratios has remained …