Introduction In patients with severe sepsis and septic shock as cause of Intensive Care Unit
(ICU) admission, we analyze the impact on mortality of adequate antimicrobial therapy …

Introduction Sepsis is a leading cause of admission to non-cardiological intensive care units
(ICUs) and the second leading cause of death among ICU patients. We present the first …

Background Sepsis is common, deadly, and heterogenous. Prior analyses of patients with
sepsis and septic shock in New York State showed a risk-adjusted association between …

Introduction Severe sepsis is a dreaded consequence of infection and necessitates
intensive care treatment. Severe sepsis has a profound impact on mortality and on hospital …

Introduction Due to the increasing burden on hospital systems, most elderly patients with
non-surgical sepsis are admitted to general internal medicine departments. Disease-severity …

Introduction Although early institution of adequate antimicrobial therapy is lifesaving in
sepsis patients, optimal antimicrobial strategy has not been established. Moreover, the …

Introduction Genetic variations may influence clinical outcomes in patients with sepsis. The
present study was conducted to evaluate the impact on mortality of three polymorphisms …

Background Sepsis is a leading cause of mortality and critical illness worldwide and is
associated with an increased mortality rate in the months following hospital discharge. The …

Introduction There are few data related to the effects of different sources of infection on
outcome. We used the Sepsis Occurrence in Acutely ill Patients (SOAP) database to …

Introduction The impact of gender on outcome in critically ill patients is unclear.
Weinvestigated the influence of gender on the epidemiology of severe sepsis andassociated …