Introduction To evaluate the impact of compliance with a core version of the Surviving
Sepsis Campaign 6-hour bundle on 28 days mortality. Methods Cohort, multi-centre …

Introduction Our aim was to define early changes of lymphocytes and of NK cells in severe
sepsis and to correlate them with serum levels of soluble triggering receptor expressed on …

Introduction Intravenous fluid administration is an essential component of sepsis
management, but a positive fluid balance has been associated with worse prognosis. We …

Introduction Although many sepsis biomarkers have shown promise in selected patient
groups, only C-reactive protein and procalcitonin (PCT) have entered clinical practice. The …

Introduction Neural networks are new methodological tools based on nonlinear models.
They appear to be better at prediction and classification in biological systems than do …

Methods An observational cohort study in a medical ICU in a tertiary medical center. Patients
were prospectively identified with septic shock who did not have ALI at the outset, excluding …

Background To be able to diagnose and treat sepsis better it is important not only to improve
the knowledge about definitions and pathophysiology, but also to gain more insight into …

Background Timely administration of antibiotics is one of the most important interventions in
reducing mortality in sepsis. However, administering antibiotics within a strict time threshold …

Background Time to antibiotic administration is a key element in sepsis care; however, it is
difficult to implement sepsis care bundles. Additionally, sepsis is different from other …

Introduction Increasing antimicrobial costs, reduced development of novel antimicrobials,
and growing antimicrobial resistance necessitate judicious use of available agents …