Determination of absorption changes from moments of distributions of times of flight of photons: optimization of measurement conditions for a two-layered tissue model

A Liebert, H Wabnitz, C Elster - Journal of Biomedical Optics, 2012 - spiedigitallibrary.org
Time-resolved near-infrared spectroscopy allows for depth-selective determination of
absorption changes in the adult human head that facilitates separation between cerebral …

Time-resolved multidistance near-infrared spectroscopy of the adult head: intracerebral and extracerebral absorption changes from moments of distribution of times of …

A Liebert, H Wabnitz, J Steinbrink, H Obrig, M Möller… - Applied …, 2004 - opg.optica.org
We report on multidistance time-resolved diffuse reflectance spectroscopy of the head of a
healthy adult after intravenous administration of a bolus of indocyanine green. Intracerebral …

Intra-and extracerebral changes of hemoglobin concentrations by analysis of moments of distributions of times of flight of photons

A Liebert, H Wabnitz, J Steinbrink, H Obrig… - … on Biomedical Optics, 2003 - opg.optica.org
NIRS signals measured on the adult head contain contributions from the brain and from
overlying tissue. It was shown recently that measured distributions of times of flight (DTOF) of …

[PDF][PDF] In vivo quantification of absorption changes in the human brain by time-domain diffuse near-infrared spectroscopy

A Jelzow - 2013 - depositonce.tu-berlin.de
Measurement of the brain activity is essential for the understanding of brain function and
potentially for the diagnosis of brain pathologies. Human brain activity is accompanied by …

Evaluation of optical properties of highly scattering media by moments of distributions of times of flight of photons

A Liebert, H Wabnitz, D Grosenick, M Möller… - Applied …, 2003 - opg.optica.org
A novel method for the determination of the optical properties of tissue from time-domain
measurements is presented. The data analysis is based on the evaluation of the first …

Improving the depth sensitivity of time-resolved measurements by extracting the distribution of times-of-flight

M Diop, K St. Lawrence - Biomedical optics express, 2013 - opg.optica.org
Time-resolved (TR) techniques provide a means of discriminating photons based on their
time-of-flight. Since early arriving photons have a lower probability of probing deeper tissue …

Reconstruction of light absorption changes in the human head using analytically computed photon partial pathlengths in layered media

DA Vera, HA García, MV Waks-Serra, NA Carbone… - JOSA A, 2023 - opg.optica.org
Functional near infrared spectroscopy has been used in recent decades to sense and
quantify changes in hemoglobin concentrations in the human brain. This noninvasive …

Low-resolution mapping of the effective attenuation coefficient of the human head: a multidistance approach applied to high-density optical recordings

AM Chiarelli, EL Maclin, KA Low, S Fantini… - …, 2017 - spiedigitallibrary.org
Near infrared (NIR) light has been widely used for measuring changes in hemoglobin
concentration in the human brain (functional NIR spectroscopy, fNIRS). fNIRS is based on …

Time-resolved absorption and hemoglobin concentration difference maps: a method to retrieve depth-related information on cerebral hemodynamics.

B Montcel, R Chabrier, P Poulet - Optics Express, 2006 - opg.optica.org
Time-resolved diffuse optical methods have been applied to detect hemodynamic changes
induced by cerebral activity. We describe a near infrared spectroscopic (NIRS) …

Determining changes in NIR absorption using a layered model of the human head

J Steinbrink, H Wabnitz, H Obrig… - Physics in Medicine …, 2001 - iopscience.iop.org
A theoretical approach is presented to determine absorption changes in different
compartments of a layered structure from distributions of times of flight of photons. In addition …