[HTML][HTML] NADPH oxidases and oxidative stress in the pathogenesis of atrial fibrillation

R Ramos-Mondragón, A Lozhkin, AE Vendrov… - Antioxidants, 2023 - mdpi.com
Atrial fibrillation (AF) is the most common type of cardiac arrhythmia and its prevalence
increases with age. The irregular and rapid contraction of the atria can lead to ineffective …

Oxidative stress in atrial fibrillation: an emerging role of NADPH oxidase

JY Youn, J Zhang, Y Zhang, H Chen, D Liu… - Journal of molecular and …, 2013 - Elsevier
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Patients with AF have up to
seven-fold higher risk of suffering from ischemic stroke. Better understanding of etiologies of …

Mechanisms and treatments of oxidative stress in atrial fibrillation

X Ren, X Wang, M Yuan, C Tian, H Li… - Current …, 2018 - ingentaconnect.com
Atrial fibrillation (AF) is a frequent cardiac arrhythmia. It is a common major cause of serious
diseases and is an increasing health-care burden. AF is associated with an excess amount …

Redox control of cardiac remodeling in atrial fibrillation

C Wolke, A Bukowska, A Goette, U Lendeckel - Biochimica et Biophysica …, 2015 - Elsevier
Background Atrial fibrillation (AF) is the most common arrhythmia in clinical practice and is a
potential cause of thromboembolic events. AF induces significant changes in the …

The role of oxidative stress in the pathogenesis and perpetuation of atrial fibrillation

P Korantzopoulos, TM Kolettis, D Galaris… - International journal of …, 2007 - Elsevier
Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice
representing a major health hazard. Owing to relative inefficacy and side effects of classic …

Activation of NADPH oxidase mediates mitochondrial oxidative stress and atrial remodeling in diabetic rabbits

L Zhou, Y Liu, Z Wang, D Liu, B Xie, Y Zhang, M Yuan… - Life Sciences, 2021 - Elsevier
Aims The mechanisms of atrial fibrillation (AF) in diabetes mellitus (DM) involve a complex
interplay between increased oxidative stress, mitochondrial dysfunction and atrial …

Compromised redox homeostasis, altered nitroso–redox balance, and therapeutic possibilities in atrial fibrillation

JN Simon, K Ziberna, B Casadei - Cardiovascular research, 2016 - academic.oup.com
Although the initiation, development, and maintenance of atrial fibrillation (AF) have been
linked to alterations in myocyte redox state, the field lacks a complete understanding of the …

Mitochondrial dysfunction and redox signaling in atrial tachyarrhythmia

A Bukowska, L Schild, G Keilhoff… - Experimental …, 2008 - journals.sagepub.com
Accumulating evidence links calcium-overload and oxidative stress to atrial remodeling
during atrial fibrillation (AF). Furthermore, atrial remodeling appears to increase atrial …

Selective downregulation of mitochondrial electron transport chain activity and increased oxidative stress in human atrial fibrillation

L Emelyanova, Z Ashary, M Cosic… - American Journal …, 2016 - journals.physiology.org
Mitochondria are critical for maintaining normal cardiac function, and a deficit in
mitochondrial energetics can lead to the development of the substrate that promotes atrial …

[HTML][HTML] Developing Pharmacological Therapies for Atrial Fibrillation Targeting Mitochondrial Dysfunction and Oxidative Stress: A Scoping Review

AS Menezes Júnior, ALG França-e-Silva… - International Journal of …, 2023 - mdpi.com
Atrial fibrillation (AF) is a cardiac arrhythmia caused by electrophysiological anomalies in the
atrial tissue, tissue degradation, structural abnormalities, and comorbidities. A direct …