Safety of apixaban for venous thromboembolism prophylaxis: the evidence to date

V Trkulja - Drug, Healthcare and Patient Safety, 2016 - Taylor & Francis
Apixaban, a direct orally active anticoagulant (selective, direct factor Xa inhibitor) is
approved for (primary) prevention of venous thromboembolism (VTE) in patients undergoing …

Apixaban: a review of its use in the prevention of venous thromboembolism after knee or hip replacement surgery

ED Deeks - Drugs, 2012 - Springer
Apixaban (Eliquis™) is an orally active and selective direct inhibitor of factor Xa indicated for
twice-daily use in the EU for the prevention of venous thromboembolism (VTE) in adults who …

Apixaban: first global approval

J Watson, G Whiteside, C Perry - Drugs, 2011 - Springer
Apixaban (Eliquis™), an oral direct factor Xa inhibitor, is being developed by Bristol-Myers
Squibb and Pfizer as a therapy for the prevention and/or treatment of thrombotic disorders …

Therapeutic potential of apixaban in the prevention of venous thromboembolism in patients undergoing total knee replacement surgery

D Imberti, M Gallerani, R Manfredini - Journal of thrombosis and …, 2012 - Springer
Anticoagulant prophylaxis for preventing venous thromboembolism (VTE) is a worldwide
established procedure in hip and knee replacement surgery. Despite available …

The role of apixaban for venous and arterial thromboembolic disease

R Prom, SA Spinler - Annals of Pharmacotherapy, 2011 - journals.sagepub.com
Objective: To provide a comprehensive review of the pharmacology, pharmacokinetics,
pharmacodynamics, clinical trial data, adverse effects, and drug interactions of apixaban …

Therapeutic potential of apixaban in the prevention of venous thromboembolism in patients undergoing total knee replacement surgery

MT Martin, EA Nutescu - Current medical research and opinion, 2011 - Taylor & Francis
Background: Apixaban is a novel oral factor Xa inhibitor that recently completed evaluation
in clinical trials for its use in the prevention of venous thromboembolism (VTE) in patients …

The safety and efficacy of apixaban: where do we stand in 2013?

F de Souza Brito, RD Lopes… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Traditional oral anticoagulants, such as warfarin, are effective but require
frequent laboratory monitoring for dose adjustment and have several known interactions …

[HTML][HTML] Apixaban after hip or knee arthroplasty versus enoxaparin: efficacy and safety in key clinical subgroups

GF Pineo, AS Gallus, GE Raskob, D Chen… - Journal of Thrombosis …, 2013 - Elsevier
Background: New oral anticoagulants for thromboprophylaxis after hip or knee arthroplasty
have been given as fixed-dose regimens. Objective: To evaluate the consistency of the …

[HTML][HTML] Apixaban Versus Enoxaparin for Thromboprophylaxis After Joint Replacement Surgery: Pooled Analysis of Major Venous Thromboembolism and Bleeding In …

GE Raskob, AS Gallus, GF Pineo, D Chen, LM Ramirez… - Blood, 2010 - Elsevier
Abstract 192 Thromboprophylaxis after joint replacement surgery is evidence-based
standard care. Usually, when thromboprophylaxis regimens with new anticoagulants have …

Practical use of apixaban in the prevention of venous thromboembolism after total knee or hip replacement.

MR Lassen - Drugs of Today (Barcelona, Spain: 1998), 2012 - europepmc.org
Apixaban is an anticoagulant drug that acts by directly inhibiting coagulation factor Xa.
Unlike low-molecular-weight heparins and fondaparinux, apixaban can be taken orally; in …