Cell death pathways: intricate connections and disease implications

M Kist, D Vucic - The EMBO Journal, 2021 - embopress.org
Various forms of cell death have been identified over the last decades with each relying on a
different subset of proteins for the activation and execution of their respective pathway (s). In …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

L Galluzzi, I Vitale, SA Aaronson, JM Abrams… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

The molecular machinery of regulated cell death

D Tang, R Kang, TV Berghe, P Vandenabeele… - Cell research, 2019 - nature.com
Cells may die from accidental cell death (ACD) or regulated cell death (RCD). ACD is a
biologically uncontrolled process, whereas RCD involves tightly structured signaling …

Apoptosis, pyroptosis, and necroptosis—Oh my! The many ways a cell can die

N Ketelut-Carneiro, KA Fitzgerald - Journal of molecular biology, 2022 - Elsevier
Cell death is an essential process in all living organisms and occurs through different
mechanisms. The three main types of programmed cell death are apoptosis, pyroptosis, and …

[HTML][HTML] Multiple cell death modalities and their key features

GE Yan, M Elbadawi, T Efferth - World …, 2020 - … .spandidos-publications.com
Cell death, as a final cellular decision which is reached following complex communications,
represents a critical process with which to maintain organismic homeostasis. Different …

A guide to cell death pathways

J Yuan, D Ofengeim - Nature Reviews Molecular Cell Biology, 2024 - nature.com
Regulated cell death mediated by dedicated molecular machines, known as programmed
cell death, plays important roles in health and disease. Apoptosis, necroptosis and …

Overview of cell death signaling pathways

Z Jin, WS El-Deiry - Cancer biology & therapy, 2005 - Taylor & Francis
Apoptosis plays an important role in development and maintenance of tissue homeostasis.
Intensive efforts have been made to explore the molecular mechanisms of the apoptotic …

Diversity and complexity of cell death: a historical review

W Park, S Wei, BS Kim, B Kim, SJ Bae… - … & molecular medicine, 2023 - nature.com
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

Regulated cell death: discovery, features and implications for neurodegenerative diseases

J Cui, S Zhao, Y Li, D Zhang, B Wang, J Xie… - Cell Communication and …, 2021 - Springer
Regulated cell death (RCD) is a ubiquitous process in living organisms that is essential for
tissue homeostasis or to restore biological balance under stress. Over the decades, various …

The independence of and associations among apoptosis, autophagy, and necrosis

Q Chen, J Kang, C Fu - Signal transduction and targeted therapy, 2018 - nature.com
Cell death is an essential biological process for physiological growth and development.
Three classical forms of cell death—apoptosis, autophagy, and necrosis—display distinct …