LEARNING OBJECTIVES: Reading this article will reinforce the reader's knowledge of the
definition, pathophysiology, differential diagnosis, and treatment of the steroid-resistant …

Asthma is usually a steroid responsive disease. A few patients respond poorly to these
drugs, and others need such high doses to control the disease that side-effects become a …

In the past decade, numerous studies have established that inflammation and immune
activation play a critical role in the pathogenesis of airway obstruction and bronchial …

Introduction: For decades glucocorticoids have been considered as the gold standard for the
treatment of asthma. We present a case report of typical glucocorticoid-resistant asthma and …

Although most patients with chronic asthma respond to corticosteroid therapy, a small subset
of asthmatics are unresponsive to corticosteroids and demonstrate persistent airway …

Glucocorticoids play an important role in asthma therapy; however, a subset of patients are
poorly responsive. We evaluated immunologic and pharmacologic features of 17 patients …

Glucocorticoids are currently the most effective anti-inflammatory therapy for asthma.
However, a small subset of asthma sufferers do not respond to clinically relevant doses of …

Glucocorticoids are highly effective in the control of asthma and other chronic inflammatory
or immune diseases. The value of steroids in asthma became apparent soon after the …

Although the majority of patients with asthma respond favorably to inhaled and systemic
glucocorticoids, up to 25% of patients with difficult-to-control asthma have poor clinical …

Glucocorticoids (GC) have been used in the treatment of inflammatory disorders, including
asthma, for approximately 50 years (12). Both clinical and anti-inflammatory effects were …