To discover novel anticancer agents with potent and low toxicity, we designed and
synthesized a range of new thiosemicarbazone-indole analogues based on lead compound …

Potent and safe anticancer drugs research and development are still on the way to human
health. In this report, a series of novel thiosemicarbazone derivatives containing indole …

Abstract Novel thiourea (5a, 5b) and thiazolidinone derivatives (6a, 6b) were synthesized by
hybridizing molecules starting from the compound 6‐(4‐phenylpiperazin‐1‐yl) pyridin‐3 …

Thiosemicarbazones have been the focus of scientists owing to their broad clinical
anticancer range. Herein, A Series of new thiosemicarbazone derivatives 5–9 were …

Thiosemicarbazones play a pivotal role as potential therapeutic agents for the management
of lung cancer. 4-(4-Cyanophenyl)-1-[(5-arylfuran-2-yl) methylene] thiosemicarbazides (1 …

A series of 2, 5-disubstituted-thiazolidine-2, 4-dione analogs based on the newly identified
lead 1, a potential anticancer agent via the inhibition of the Raf/MEK/extracellular signal …

In this paper, a series of thiosemicarbazone derivatives containing different aromatic
heterocyclic groups were synthesized and the tridentate donor system of the lead compound …

In this work, two novel series of indole‐thiosemicarbazone derivatives were designed,
synthesized, and evaluated for their cytotoxic activity against MCF‐7, A‐549, and Hep‐G2 …

Abstract P-glycoprotein (P-gp)-mediated multidrug resistance (MDR) is a major obstacle to
successful chemotherapy for leukemia. In this study, a series of thiosemicarbazone …

A variety of novel thiazolidin‐4‐one himachalene derivatives were designed and
synthesized through hetero‐cyclization of thiosemicarbazone analogs that have previously …