Treatment of acute lung injury: historical perspective and potential future therapies

JE Levitt, MA Matthay - Seminars in respiratory and critical care …, 2006 - thieme-connect.com
The acute respiratory distress syndrome (ARDS) was first described by Ashbaugh and
colleagues in 1967. However, despite considerable efforts, early progress in treatment was …

Acute respiratory distress syndrome: a clinical review

M Donahoe - Pulmonary circulation, 2011 - journals.sagepub.com
The acute respiratory distress syndrome (ARDS) is a complex disorder of heterogeneous
etiologies characterized by a consistent, recognizable pattern of lung injury. Extensive …

Rethinking acute respiratory distress syndrome after COVID-19: if a “better” definition is the answer, what is the question?

VM Ranieri, G Rubenfeld, AS Slutsky - American Journal of …, 2023 - atsjournals.org
The definition of acute respiratory distress syndrome (ARDS) has a somewhat controversial
history, with some even questioning the need for the term “ARDS.” This controversy has …

Epidemiology of ARDS and ALI

R Blank, LM Napolitano - Critical care clinics, 2011 - criticalcare.theclinics.com
Acute respiratory distress syndrome (ARDS) and acute lung injury (ALI) are distinctly
modern clinical entities. First described in 1967 1 and codified by a consensus of experts in …

Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

LDJ Bos, LB Ware - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is a common clinical syndrome of acute
respiratory failure as a result of diffuse lung inflammation and oedema. ARDS can be …

Epidemiological characteristics, practice of ventilation, and clinical outcome in patients at risk of acute respiratory distress syndrome in intensive care units from 16 …

AS Neto, CSV Barbas, FD Simonis… - The Lancet …, 2016 - thelancet.com
Background Scant information exists about the epidemiological characteristics and outcome
of patients in the intensive care unit (ICU) at risk of acute respiratory distress syndrome …

The acute respiratory distress syndrome: Diagnosis and management

D Chiumello, A Marino, A Cammaroto - Practical Trends in Anesthesia and …, 2019 - Springer
Acute respiratory distress syndrome (ARDS) is characterized by a new acute onset of
hypoxemia secondary to a pulmonary edema of non-cardiogenic origin, bilateral lung …

Clinical trials in acute respiratory distress syndrome: challenges and opportunities

MA Matthay, DF McAuley, LB Ware - The Lancet Respiratory …, 2017 - thelancet.com
This year is the 50th anniversary of the first description of acute respiratory distress
syndrome (ARDS). Since then, much has been learned about the pathogenesis of lung …

Pulmonary and extrapulmonary acute respiratory distress syndrome: myth or reality?

PRM Rocco, P Pelosi - Current opinion in critical care, 2008 - journals.lww.com
Heterogeneous acute respiratory distress syndrome patients are still considered to suffer
from one syndrome, and are treated in the same way. Understanding the range of different …

Precision medicine in acute respiratory distress syndrome: workshop report and recommendations for future research

LDJ Bos, A Artigas, JM Constantin… - European …, 2021 - Eur Respiratory Soc
Acute respiratory distress syndrome (ARDS) is a devastating critical illness that can be
triggered by a wide range of insults and remains associated with a high mortality of around …